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- W2384985320 abstract "Aim To observe the clinical effect of atrovastatin on the patients of coronary slow flow.Methods A total of 75 patients with coronary slow flow and chest pain were randomly divided into 2 groups.The trial group(atrovastatin 20mg/d for half a year,n=45)was treated with atrovastatin and another group(n=30)was treated with the same drugs except atrovastatin.28 healthy subjects with normal angiography and chest pain but negative exercise ECG acted as norml controls.hs-CRP、ET-1 and IL-6 were measured with ELISA.NO was measured with chromatometry.Results TIMI frame counts in statin group and non-statin group were significantly higher than those in control group through coronary angiography.Half a year later,TIMI frame counts in statin group and control group were significantly lower than those in non-statin group through coronary angiography.Half a year later,TG and HDL-c were similar in three groups,total cholesterol and LDL-c levels were significantly lower in statin group than those in non-statin group and control group.Multivarible analysis showed that hs-CRP,ET-1,IL-6 and NO were risk factors of CSF.The total effective rate of treatment with atrovastatin was 84% in statin group.Conclusion It showed that atrovastatin not only decreases lipid,have effect of antiinflammation and protecting endothelium,but also improves patients'clinical symptom with coronary slow flow." @default.
- W2384985320 created "2016-06-24" @default.
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- W2384985320 date "2011-01-01" @default.
- W2384985320 modified "2023-09-23" @default.
- W2384985320 title "Clinical effect of atrovastatin on coronary slow flow" @default.
- W2384985320 hasPublicationYear "2011" @default.
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