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- W2385028730 abstract "Objective To explore the effects of dendritic cells (DC) on synovial membranes in patients with rheumatoid arthritis (RA).Methods The number and the distribution of HLA DR +,S 100 + and CD1a + cells on synovial membranes in 25 patients with rheumatoid arthritis were investigated with immunohistochemical staining.Results The case percentages of HLA DR,S 100 and CD1a positive expression on synovial membranes in patients with RA were higher those that in the control.The positive numbers of patients with RA were 23,19 and 16 respectively.The number of HLA DR +,S 100 + and CD1a + cells on synovial membranes were very significantly higher in patients with RA than in the control ( P 0 01).Conclusion The existence and the incremental numbers of DC,activated DC and HLA DR + cells may play an important role in the procedure of submitting autoantigens is the local lesion of RA.It is an important and beginning factor for the abnormal autoimmunity of RA." @default.
- W2385028730 created "2016-06-24" @default.
- W2385028730 creator A5087761431 @default.
- W2385028730 date "2003-01-01" @default.
- W2385028730 modified "2023-09-25" @default.
- W2385028730 title "Dendritic cells on synovial membranes in patients with rheumatoid arthritis" @default.
- W2385028730 hasPublicationYear "2003" @default.
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