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- W2385072016 abstract "Objective:To study the imaging findings of severe influenza A (H1N1) infection. Methods:The imaging materials of 76 patients with severe influenza A (H1N1) were retrospectively analyzed.All of the patients were divided into three groups based on the clinical course.Group 1 (n=50) included the patients either treated as out-patients or with short hospitalization.Group 2 (n=14) included patients with acute respiratory distress syndrome (ARDS) but without advanced mechanical ventilation.Group 3 (n=12) included patients with acute respiratory failure and advanced mechanical ventilation was required.The chest radiographic and CT findings including the size,morphology,number and distribution of the pulmonary lesions were analyzed.Results:The main imaging findings of severe influenza A (H1N1) infection were unilateral/bilateral pulmonary ground-glass opacities (GGO),consolidation or mixed pattern.In Group 1,GGO was the major features,generally showed multiple lesions,all pulmonary lobes but mainly bilateral lower lobes could be involved,mostly located at the periphery of lung.Consolidation was the main finding in Group 2,might be associated with GGO or focal consolidations.Fibrosis was assessed in the recovering stage of a few patients.The most common pattern of Group 3 was pulmonary consolidation,might be associated with interstitial changes.Simple GGO was uncommon.Pleural/pericardial effusion and pulmonary atelectasis might be revealed in some of the patients.Secondary pneumothorax,pneumomediastinum,subcutaneous emphysema and fungal infection,secondary pulmonary hypertension,right heart failure,liver and spleen congestion could be complicated in Group 3 patients.Conclusion:Different imaging manifestations could be revealed in different clinical stages of influenza A (H1N1) patients.The imaging manifestations were in a minor extent in mild type of infection,complete recovery could be obtained.Fibrosis could be seen in some serious patients.For critical, especially those required mechanical ventilation,repeatedly relapse of the disease could be assessed.In the advanced stage,following-up radiography in time is helpful to evaluate the course of illness,and play an important role in the guidance of appropriate treatment." @default.
- W2385072016 created "2016-06-24" @default.
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- W2385072016 date "2010-01-01" @default.
- W2385072016 modified "2023-09-26" @default.
- W2385072016 title "Manifestations and dynamic observation of imaging findings in 76 patients with severe influenza A (H1N1) viral infection" @default.
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