Matches in SemOpenAlex for { <https://semopenalex.org/work/W2385086310> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W2385086310 abstract "Objective:To compare the efficacy and safety of oral ibuprofen and indomethacin for the early treatment of patent ductus arteriosus in premature infants.Methods:30 cases of infants with gestational ages of 30～35 weeks and color doppler echocardiograhpically confirmed PDA, were randomly assigned into two groups to receive either oral ibuprofen suspension (a first dose of 10 mg per kilogram, followed at 24-hour intervals by two doses of 5 mg per kilogram each) or oral indomethacin (0.2 mg per kilogram of body weight, given at 12-hour intervals) starting on the third day of life.Results:The rate of ductul closure was similar with the two treatments: PDA closed in 12 of 15 patients from the ibuprofen group(80%),and in 13 of 15 from indomethacin group(87%).There was no significant difference between two groups(P0.05). Oliguria occurred in 3 infants treated with ibuprofen and in 10 treated with indomethacin.5 cases of increase in serum creatinine and 6 cases of blood urea nitrogen in indomethacin group whereas 1 case of increase in serum creatinine and 0 case of blood urea nitrogen in ibuprofen group. There was significant difference about urinary output, serum creatinine and blood urea nitrogen between two groups(P0.05)。 No significant differences with respect to other side effects or complications. There were 2 cases of occult bleeding in stool and 1 case of increased serum total bilirubin in indomethacin group. No abdominal distension and necrotizing enterocolitis.Conclusion:Oral ibuprofen therapy on the third day of life is as efficacious as indomethacin for the treatment of patent ductus arteriosus in premature infants and is significantly less likely to induce oliguria and renal failure." @default.
- W2385086310 created "2016-06-24" @default.
- W2385086310 creator A5012917873 @default.
- W2385086310 date "2005-01-01" @default.
- W2385086310 modified "2023-09-27" @default.
- W2385086310 title "The efficacy and safety of oral ibuprofen and indomethacin for the treatment of patent ductus arteriosus in premature infants" @default.
- W2385086310 hasPublicationYear "2005" @default.
- W2385086310 type Work @default.
- W2385086310 sameAs 2385086310 @default.
- W2385086310 citedByCount "0" @default.
- W2385086310 crossrefType "journal-article" @default.
- W2385086310 hasAuthorship W2385086310A5012917873 @default.
- W2385086310 hasConcept C126322002 @default.
- W2385086310 hasConcept C141071460 @default.
- W2385086310 hasConcept C159641895 @default.
- W2385086310 hasConcept C2777513400 @default.
- W2385086310 hasConcept C2778176769 @default.
- W2385086310 hasConcept C2779124032 @default.
- W2385086310 hasConcept C2779303187 @default.
- W2385086310 hasConcept C2779744138 @default.
- W2385086310 hasConcept C2779944601 @default.
- W2385086310 hasConcept C2780306776 @default.
- W2385086310 hasConcept C2781236024 @default.
- W2385086310 hasConcept C42219234 @default.
- W2385086310 hasConcept C71924100 @default.
- W2385086310 hasConcept C90924648 @default.
- W2385086310 hasConcept C98274493 @default.
- W2385086310 hasConceptScore W2385086310C126322002 @default.
- W2385086310 hasConceptScore W2385086310C141071460 @default.
- W2385086310 hasConceptScore W2385086310C159641895 @default.
- W2385086310 hasConceptScore W2385086310C2777513400 @default.
- W2385086310 hasConceptScore W2385086310C2778176769 @default.
- W2385086310 hasConceptScore W2385086310C2779124032 @default.
- W2385086310 hasConceptScore W2385086310C2779303187 @default.
- W2385086310 hasConceptScore W2385086310C2779744138 @default.
- W2385086310 hasConceptScore W2385086310C2779944601 @default.
- W2385086310 hasConceptScore W2385086310C2780306776 @default.
- W2385086310 hasConceptScore W2385086310C2781236024 @default.
- W2385086310 hasConceptScore W2385086310C42219234 @default.
- W2385086310 hasConceptScore W2385086310C71924100 @default.
- W2385086310 hasConceptScore W2385086310C90924648 @default.
- W2385086310 hasConceptScore W2385086310C98274493 @default.
- W2385086310 hasLocation W23850863101 @default.
- W2385086310 hasOpenAccess W2385086310 @default.
- W2385086310 hasPrimaryLocation W23850863101 @default.
- W2385086310 hasRelatedWork W1577604684 @default.
- W2385086310 hasRelatedWork W1985253648 @default.
- W2385086310 hasRelatedWork W2009596355 @default.
- W2385086310 hasRelatedWork W2026939280 @default.
- W2385086310 hasRelatedWork W2027882816 @default.
- W2385086310 hasRelatedWork W2027918458 @default.
- W2385086310 hasRelatedWork W2029730630 @default.
- W2385086310 hasRelatedWork W2031726853 @default.
- W2385086310 hasRelatedWork W2032329657 @default.
- W2385086310 hasRelatedWork W2049333710 @default.
- W2385086310 hasRelatedWork W2075095509 @default.
- W2385086310 hasRelatedWork W2082203002 @default.
- W2385086310 hasRelatedWork W2413219936 @default.
- W2385086310 hasRelatedWork W2425860547 @default.
- W2385086310 hasRelatedWork W2808729813 @default.
- W2385086310 hasRelatedWork W2997076854 @default.
- W2385086310 hasRelatedWork W3029747470 @default.
- W2385086310 hasRelatedWork W3093362010 @default.
- W2385086310 hasRelatedWork W55195160 @default.
- W2385086310 hasRelatedWork W2186769576 @default.
- W2385086310 isParatext "false" @default.
- W2385086310 isRetracted "false" @default.
- W2385086310 magId "2385086310" @default.
- W2385086310 workType "article" @default.