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- W2385189719 abstract "Objective To study the rnechanisrns of liver metastasis after radical sugery of livercancer.Methods A mouse model of experimental liver cancer metastasis was established by injectingH22 cells, a metastatic mouse hepatoma ascites tumor line, into the spleen of NIH mice, and partial hepatectomy was performed. Tumor cell adhesion and liver metastasis were observed and compared consecutively between the mice with single intrasplenic inoculation and partial hepatectomy. Results Tumorcell adhesion to endothelial cell of blood capillary of liver or sinus hepaticus was found 48~72 h aftersingle intrasplenic inoculation. Compared to single intrasplenic inoculation, earlier and more remarkablemetastases were found in mice with partial hepatectomy. Concluslon Factors of surgical trauma maybe advantageous to tumor cells adhesion to endothelial cells, which is involved in liver metastasis-enhancing effects after radical surgery of liver cancer." @default.
- W2385189719 created "2016-06-24" @default.
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- W2385189719 date "1999-01-01" @default.
- W2385189719 modified "2023-09-25" @default.
- W2385189719 title "Tumor cell adhesion and hepatic metastasis after experimental partial liver excision" @default.
- W2385189719 hasPublicationYear "1999" @default.
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