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- W2385202328 abstract "To investigate changes of NK cell subsets in HIV-infected Chinese patients,PBMCs were collected from four groups representing different stages of HIV disease:asymptomatic chronically infected HIV patients,AIDS patients,HIV-positive patients receiving highly active antiretroviral therapy(HAART),and HIV-negative controls.PBMCs were stained with fluorescent monoclonal antibodies for the NK cell subsets.Three distinct subpopulations(CD56-CD16+,CD56dimCD16+ and CD56briCD16-/+) of NK cells were quantified by flow cytometer and compared among the groups.The percentage of CD56dimCD16+ NK cells was decreased significantly,while the percentage of CD56-CD16+ and CD56briCD16-/+ NK cells were increased significantly in HIV group and AIDS group.The percentage of CD56dimCD16+,CD56-CD16+,and CD56briCD16-/+ NK cells in HAART treatment group revealed no significant differences compared to any of the groups.Our results indicate that HIV infection changes the composition of NK cell subsets,and this change can be partially restored by HAART treatment." @default.
- W2385202328 created "2016-06-24" @default.
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- W2385202328 date "2010-01-01" @default.
- W2385202328 modified "2023-09-23" @default.
- W2385202328 title "Alteration of NK cell subsets in HIV-infected Chinese" @default.
- W2385202328 hasPublicationYear "2010" @default.
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