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- W2385204310 abstract "Objective To investigate synthesis of medium substituted degree hydroxypropyl-β-cyclodextrins and the complex forming capability of dexamethasone.Methods Medium substituted degree hydroxypropyl-β-cyclodextrins were prepared and tested by pharmacopoeia.Dexamethasone were included with the product and performed by the phase-solubility diagram.Results The substituted degree of hydroxypropyl-β-cyclodextrins were 7.875.Dexamethasone was formed a 11 molar ratio inclusion complex with the product and improved solubility about 33 times.Conclusion The product accord with the request of pharmacopoeia.The dissolution capability of dexamethasone was increased by hydroxypropyl-β-cyclodextrins." @default.
- W2385204310 created "2016-06-24" @default.
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- W2385204310 date "2010-01-01" @default.
- W2385204310 modified "2023-09-26" @default.
- W2385204310 title "The complex forming ability of medium substituted degree hydroxypropyl-β-cyclodextrins on dexamethasone" @default.
- W2385204310 hasPublicationYear "2010" @default.
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