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- W2385216937 abstract "Objective To investigate the possibility of the rat mesenchymal stem cells (MSCs) induced by hepatocyte growth factor plus E growth factor to provide a seed cell for cell transplantt to cure all kinds of acute hepatic injury. Methods D-galactosamine was injected to abdominal cavity in the rat so as to duplicate liver injury model. Rat was divided into two groups, the experimental group and control group. In the experimental group,mesenchymal stem cells induced by HGF plus EGF, were transplanted into injured portal vein in the rat; in the two group, mesenchymal stem cells were transplanted into injured portal vein in the rat. After rats were put to death on 1, 3, 7 and 14 d respectively, ALT,AST , TBiL and ALP were detected in the blood; section was proceeded to routine pathology. Result Blood biochemistry results show that there is different significance in the two groups. Pathological findings display that in the experimental group hepatic degeneration and necrosis level is obviously lighter than that in the control group, in particular, at 3 and 4 days. Conclusion In addition to, when induced mesenchymal stem cells are transplanted into injured liver, to some extent, they can save the liver and repair the injured liver function." @default.
- W2385216937 created "2016-06-24" @default.
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- W2385216937 date "2008-01-01" @default.
- W2385216937 modified "2023-09-24" @default.
- W2385216937 title "Experimental study of biochemistry and pathology to recovery acute hepatic injury by transplantation mesenchymal stem cells induced by HGF and EGF in rat" @default.
- W2385216937 hasPublicationYear "2008" @default.
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