Matches in SemOpenAlex for { <https://semopenalex.org/work/W2385228711> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W2385228711 abstract "Objective To measure mitochondrial DNA(mtDNA)deletion from in different age groups mice and senile mice induced by D-galactose,and study the relevance between the mtDNA deletion and the aging.Methods Polymerase chain reaction technique and electrophoresis were used to examine the fragment deletion of mtDNA.Quantitation of relative band densities was performed using densitometry scanning techniques.The deletion was identified by direct sequencing analysis.Results A 4 239 bp mtDNA deletion was present in liver,cerebral cortex and hippocampus tissues from all of mice.The relative percentage contents of mtDNA deletion in various tissues increased significantly in old mice compared with young and adult mice(P0.01,respectively).The deletion of mtDNA was significantly higher in senile model mice induced by D-galactose than those of NS group mice(P0.01,respectively).Deletion was more abundant in liver than in cerebral cortex and hippocampus.Conclusion The results indicated that such 4 239 bp mtDNA deletion was a common deletion,which was more causally linked to senescence and could be a kind of molecular biomarker of senescence." @default.
- W2385228711 created "2016-06-24" @default.
- W2385228711 creator A5037582835 @default.
- W2385228711 date "2009-01-01" @default.
- W2385228711 modified "2023-09-24" @default.
- W2385228711 title "Study on mitochondrial DNA deletion in aging mice" @default.
- W2385228711 hasPublicationYear "2009" @default.
- W2385228711 type Work @default.
- W2385228711 sameAs 2385228711 @default.
- W2385228711 citedByCount "0" @default.
- W2385228711 crossrefType "journal-article" @default.
- W2385228711 hasAuthorship W2385228711A5037582835 @default.
- W2385228711 hasConcept C104317684 @default.
- W2385228711 hasConcept C134018914 @default.
- W2385228711 hasConcept C153911025 @default.
- W2385228711 hasConcept C24586158 @default.
- W2385228711 hasConcept C2781041448 @default.
- W2385228711 hasConcept C2781161787 @default.
- W2385228711 hasConcept C49105822 @default.
- W2385228711 hasConcept C522857546 @default.
- W2385228711 hasConcept C54355233 @default.
- W2385228711 hasConcept C552990157 @default.
- W2385228711 hasConcept C86803240 @default.
- W2385228711 hasConceptScore W2385228711C104317684 @default.
- W2385228711 hasConceptScore W2385228711C134018914 @default.
- W2385228711 hasConceptScore W2385228711C153911025 @default.
- W2385228711 hasConceptScore W2385228711C24586158 @default.
- W2385228711 hasConceptScore W2385228711C2781041448 @default.
- W2385228711 hasConceptScore W2385228711C2781161787 @default.
- W2385228711 hasConceptScore W2385228711C49105822 @default.
- W2385228711 hasConceptScore W2385228711C522857546 @default.
- W2385228711 hasConceptScore W2385228711C54355233 @default.
- W2385228711 hasConceptScore W2385228711C552990157 @default.
- W2385228711 hasConceptScore W2385228711C86803240 @default.
- W2385228711 hasLocation W23852287111 @default.
- W2385228711 hasOpenAccess W2385228711 @default.
- W2385228711 hasPrimaryLocation W23852287111 @default.
- W2385228711 hasRelatedWork W1967272763 @default.
- W2385228711 hasRelatedWork W1975090513 @default.
- W2385228711 hasRelatedWork W1975614370 @default.
- W2385228711 hasRelatedWork W1977821533 @default.
- W2385228711 hasRelatedWork W1980799586 @default.
- W2385228711 hasRelatedWork W1996319083 @default.
- W2385228711 hasRelatedWork W2044482413 @default.
- W2385228711 hasRelatedWork W2046089054 @default.
- W2385228711 hasRelatedWork W2051631650 @default.
- W2385228711 hasRelatedWork W2077714140 @default.
- W2385228711 hasRelatedWork W2110483280 @default.
- W2385228711 hasRelatedWork W2114969342 @default.
- W2385228711 hasRelatedWork W2304938906 @default.
- W2385228711 hasRelatedWork W2535504775 @default.
- W2385228711 hasRelatedWork W2589761434 @default.
- W2385228711 hasRelatedWork W2608952477 @default.
- W2385228711 hasRelatedWork W267241848 @default.
- W2385228711 hasRelatedWork W2975822785 @default.
- W2385228711 hasRelatedWork W560439226 @default.
- W2385228711 hasRelatedWork W3205647640 @default.
- W2385228711 isParatext "false" @default.
- W2385228711 isRetracted "false" @default.
- W2385228711 magId "2385228711" @default.
- W2385228711 workType "article" @default.