Matches in SemOpenAlex for { <https://semopenalex.org/work/W2385245280> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2385245280 abstract "Objective To investigate the effect of antisense oligodeoxynucleotides(AS-Lipo) targeting ATM on radiosensitivity for laryngeal squamous cell carcinoma(Hep-2).Methods Clonogenic survival assay was carried out to detect the survival ability of Hep-2 cells after irradiation,and flow cytometry was used to analyze the cell apoptosis.TUNEL assay was used to analyze cell apoptosis expression in Hep-2 cells transplantation tumor in nude mice.Results After the same dose radiotherapy,the survival fraction(SF) of cells treated with ATM AS-Lipo was lower than that of other groups(P0.05).After 4 Gy radiation,the apoptotic rate of the group irradiated with ATM AS-Lipo was(30.7 ± 1.31)%,which was significantly higher than that of others(P0.05).There were many apoptotic cells detected by TUNEL analysis in tumors treated with irradiation in combination with ATM AS-Lipo,which was notably more than that of irradiation alone.The AI(Apoptotic Index) for mice tumors treated with irradiation in combination with ATM AS-Lipo was(17.12 ± 4.2)%,significantly higher than that of other groups.Conclusion ATM AS-Lipo strengthens radiosensitivity for laryngeal squamous cell carcinoma in nude mice." @default.
- W2385245280 created "2016-06-24" @default.
- W2385245280 creator A5048054560 @default.
- W2385245280 date "2013-01-01" @default.
- W2385245280 modified "2023-09-23" @default.
- W2385245280 title "Effect of Down-regulated ATM Expression on Radiosensitivity for Laryngeal Squamous Cell Carcinoma in Nude Mice" @default.
- W2385245280 hasPublicationYear "2013" @default.
- W2385245280 type Work @default.
- W2385245280 sameAs 2385245280 @default.
- W2385245280 citedByCount "0" @default.
- W2385245280 crossrefType "journal-article" @default.
- W2385245280 hasAuthorship W2385245280A5048054560 @default.
- W2385245280 hasConcept C117262875 @default.
- W2385245280 hasConcept C126322002 @default.
- W2385245280 hasConcept C142724271 @default.
- W2385245280 hasConcept C1491633281 @default.
- W2385245280 hasConcept C190283241 @default.
- W2385245280 hasConcept C196795494 @default.
- W2385245280 hasConcept C203014093 @default.
- W2385245280 hasConcept C204232928 @default.
- W2385245280 hasConcept C206684579 @default.
- W2385245280 hasConcept C2777546739 @default.
- W2385245280 hasConcept C502942594 @default.
- W2385245280 hasConcept C509974204 @default.
- W2385245280 hasConcept C54355233 @default.
- W2385245280 hasConcept C553184892 @default.
- W2385245280 hasConcept C55493867 @default.
- W2385245280 hasConcept C71924100 @default.
- W2385245280 hasConcept C86803240 @default.
- W2385245280 hasConceptScore W2385245280C117262875 @default.
- W2385245280 hasConceptScore W2385245280C126322002 @default.
- W2385245280 hasConceptScore W2385245280C142724271 @default.
- W2385245280 hasConceptScore W2385245280C1491633281 @default.
- W2385245280 hasConceptScore W2385245280C190283241 @default.
- W2385245280 hasConceptScore W2385245280C196795494 @default.
- W2385245280 hasConceptScore W2385245280C203014093 @default.
- W2385245280 hasConceptScore W2385245280C204232928 @default.
- W2385245280 hasConceptScore W2385245280C206684579 @default.
- W2385245280 hasConceptScore W2385245280C2777546739 @default.
- W2385245280 hasConceptScore W2385245280C502942594 @default.
- W2385245280 hasConceptScore W2385245280C509974204 @default.
- W2385245280 hasConceptScore W2385245280C54355233 @default.
- W2385245280 hasConceptScore W2385245280C553184892 @default.
- W2385245280 hasConceptScore W2385245280C55493867 @default.
- W2385245280 hasConceptScore W2385245280C71924100 @default.
- W2385245280 hasConceptScore W2385245280C86803240 @default.
- W2385245280 hasLocation W23852452801 @default.
- W2385245280 hasOpenAccess W2385245280 @default.
- W2385245280 hasPrimaryLocation W23852452801 @default.
- W2385245280 hasRelatedWork W1956512986 @default.
- W2385245280 hasRelatedWork W2112266802 @default.
- W2385245280 hasRelatedWork W2292185418 @default.
- W2385245280 hasRelatedWork W2316508824 @default.
- W2385245280 hasRelatedWork W2348219046 @default.
- W2385245280 hasRelatedWork W2354639580 @default.
- W2385245280 hasRelatedWork W2354720491 @default.
- W2385245280 hasRelatedWork W2361654234 @default.
- W2385245280 hasRelatedWork W2368273360 @default.
- W2385245280 hasRelatedWork W2371563614 @default.
- W2385245280 hasRelatedWork W2373099415 @default.
- W2385245280 hasRelatedWork W2373293207 @default.
- W2385245280 hasRelatedWork W2374593097 @default.
- W2385245280 hasRelatedWork W2375405927 @default.
- W2385245280 hasRelatedWork W2376417932 @default.
- W2385245280 hasRelatedWork W2382237454 @default.
- W2385245280 hasRelatedWork W2580237400 @default.
- W2385245280 hasRelatedWork W3031588137 @default.
- W2385245280 hasRelatedWork W3031724978 @default.
- W2385245280 hasRelatedWork W325010993 @default.
- W2385245280 isParatext "false" @default.
- W2385245280 isRetracted "false" @default.
- W2385245280 magId "2385245280" @default.
- W2385245280 workType "article" @default.