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- W2385270328 abstract "Objective:To investigate the immune response of topical immunization of new choitosan nanoparticles coating DNA vaccine.Methods: Different DNA vaccines of Lagurus lagurus zona pellucida 3 gene(Lzp3),pcDNA3-Lzp3(pLzp3)and pLC coated with chitosan immunized NIH mice by topical immunization.The antibodies were measured by ELISA.Histology was performed on representative 8-μm sections of ovaries from immunized mice.Results: ELISA showed that the effect of the pLC coated with the chitosan was the best.Histology analysis indicated that no disruption of follicular development.Conclusion: This topical immunization using the mixture of the chitosan-DNA in comparison with the naked DNA was the more effective immunization technique." @default.
- W2385270328 created "2016-06-24" @default.
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- W2385270328 date "2006-01-01" @default.
- W2385270328 modified "2023-09-25" @default.
- W2385270328 title "Chitosan-DNA Nanoparticles Enhancing the Immune Response of Lzp3 DNA Vaccine Following the Topical Vaccination" @default.
- W2385270328 hasPublicationYear "2006" @default.
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