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- W2385277272 abstract "Objective To study the effect of oxidative invasion and apoptosis during the process of acute renal ischemical reperfusion injury.Methods The models of acute renal ischemical reperfusion injury were established by methods of resecting the left kidney of rat and blocking the right kidney pedicle in the same time,glutathione peroxidase(GSH-Px) as well as superoxide dismutase(SOD) activity and malonical aldehyde(MDA) were measured.Results Compared with control group,renal SOD activity reduced and MDA content increased significantly in different periods of acute renal ischemical reperfusion injury(P0.01 and P0.05,respectively);GSH-Px activity reduced in earlier injury period(P0.05),but recoveried in late period.The great difference of renal cells apoptosis rate was found between experiment groups and control groups;There was negative correlation between SOD activity and apoptosis,and positive correlation between MDA content and apoptosis.Conclusion Oxidative invasion during different period of acute renal ischemical reperfusion injury runs an important role in renal injury;Ischemical reperfusion injury has some correlation with oxidative invasion and apoptosis." @default.
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- W2385277272 date "2007-01-01" @default.
- W2385277272 modified "2023-09-23" @default.
- W2385277272 title "The study of oxidative invasion and apoptosis during acute renal ischemic reperfusion injury in rats" @default.
- W2385277272 hasPublicationYear "2007" @default.
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