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- W2385280064 abstract "Objective To investigate the mechanism of effects of apigenin (certain phytoestrogens) on the leydig cells of rat testis. Methods Using the technique of Percoll discontinuous density gradients centrifugation, the higher purity of leydig cells were primary cultured. The different concentrations of apigenin were used on leydig cells to investigate the releasing T. The technique of MTT, flow cytometry was used to observe the apoptosis of leydig cells. Results It was indicated that apigenin inhibited T secretion of leydig cells in dose-dependence.FCM and MTT analysis showed that apigenin promoted the apotosis rate of leydig cell and restrained the increment of leydig cells. Conclusions Apigenin could inhibit T secretion of rats leydig cells. Apigenin could also inhibit the reproduction of leydig cells and promoted their apopotis." @default.
- W2385280064 created "2016-06-24" @default.
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- W2385280064 date "2005-01-01" @default.
- W2385280064 modified "2023-09-26" @default.
- W2385280064 title "The Research on the Mechanism of the Effect of Apigenin on the Leydig Cells of Rats" @default.
- W2385280064 hasPublicationYear "2005" @default.
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