FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2385280152> ?p ?o ?g. }

• W2385280152 endingPage "788" @default.
• W2385280152 startingPage "781" @default.
• W2385280152 abstract "Levothyroxine (LT4) is the standard of care in patients with hypothyroidism. Despite this replacement therapy, quality of life (QoL) remains impaired in a substantial amount of patients. The reasons for this are still a matter of debate. Suggested causes include lack of endogenous T3 secretion by the thyroid, changes in other thyroid hormone metabolites and interference by autoimmune processes.To investigate the association between thyroid function tests (TFTs) and QoL in patients with a history of differentiated thyroid cancer on LT4 monotherapy. These patients lack endogenous thyroidal T3 secretion in the absence of autoimmune disease.This is a cross-sectional study in 143 patients (69·2% female). Initial therapy consisted of total thyroidectomy followed by radioiodine ablation minimally one year before inclusion. We assessed health-related QoL (RAND-36), thyroid-specific QoL (ThyPRO) and fatigue with the Multidimensional Fatigue Inventory. Extensive TFTs were assessed, including 3,5-diiodo-L-thyronine (3,5-T2).Mean age was 50·2 years and mean time since diagnosis was 8·4 years. Median TSH was 0·042 mU/l, total T4 145·0 nmol/l, free T4 25·6 pmol/l, total T3 1·93 nmol/l, reverse T3 0·53 nmol/l and 3,5-T2 0·86 nmol/l. Multiple linear regression analyses did not show any association between QoL and the different TFTs, including T4/T3 and 3,5-T2/T3 ratios reflecting peripheral metabolism.We did not find any association between TFTs and QoL in athyreotic patients on LT4 monotherapy. Our data do not provide evidence that a slight increase in dose improves fatigue or well-being in hypothyroid patients on LT4 therapy." @default.
• W2385280152 created "2016-06-24" @default.
• W2385280152 creator A5008141462 @default.
• W2385280152 creator A5029938462 @default.
• W2385280152 creator A5038074463 @default.
• W2385280152 creator A5048261461 @default.
• W2385280152 creator A5052536282 @default.
• W2385280152 creator A5057530833 @default.
• W2385280152 creator A5062560260 @default.
• W2385280152 creator A5064218360 @default.
• W2385280152 creator A5065935445 @default.
• W2385280152 creator A5089856275 @default.
• W2385280152 date "2016-06-13" @default.
• W2385280152 modified "2023-10-18" @default.
• W2385280152 title "Thyroid hormone and its metabolites in relation to quality of life in patients treated for differentiated thyroid cancer" @default.
• W2385280152 cites W1490058975 @default.
• W2385280152 cites W1779163430 @default.
• W2385280152 cites W1807014225 @default.
• W2385280152 cites W1835291741 @default.
• W2385280152 cites W1838537074 @default.
• W2385280152 cites W1839836563 @default.
• W2385280152 cites W1888479777 @default.
• W2385280152 cites W1936681872 @default.
• W2385280152 cites W1976880940 @default.
• W2385280152 cites W1985332654 @default.
• W2385280152 cites W1985524475 @default.
• W2385280152 cites W2003239266 @default.
• W2385280152 cites W2014700437 @default.
• W2385280152 cites W2018940624 @default.
• W2385280152 cites W2020840544 @default.
• W2385280152 cites W2021314292 @default.
• W2385280152 cites W2033152833 @default.
• W2385280152 cites W2045543558 @default.
• W2385280152 cites W2069605085 @default.
• W2385280152 cites W2074532062 @default.
• W2385280152 cites W2085495215 @default.
• W2385280152 cites W2086983947 @default.
• W2385280152 cites W2088500908 @default.
• W2385280152 cites W2091422735 @default.
• W2385280152 cites W2104695445 @default.
• W2385280152 cites W2111859264 @default.
• W2385280152 cites W2112887358 @default.
• W2385280152 cites W2120786909 @default.
• W2385280152 cites W2121784884 @default.
• W2385280152 cites W2122267743 @default.
• W2385280152 cites W2127290117 @default.
• W2385280152 cites W2130124581 @default.
• W2385280152 cites W2131840394 @default.
• W2385280152 cites W2135957727 @default.
• W2385280152 cites W2150335827 @default.
• W2385280152 cites W2152462131 @default.
• W2385280152 cites W2161376581 @default.
• W2385280152 cites W2163820892 @default.
• W2385280152 cites W2315033586 @default.
• W2385280152 doi "https://doi.org/10.1111/cen.13101" @default.
• W2385280152 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27175823" @default.
• W2385280152 hasPublicationYear "2016" @default.
• W2385280152 type Work @default.
• W2385280152 sameAs 2385280152 @default.
• W2385280152 citedByCount "35" @default.
• W2385280152 countsByYear W23852801522016 @default.
• W2385280152 countsByYear W23852801522017 @default.
• W2385280152 countsByYear W23852801522018 @default.
• W2385280152 countsByYear W23852801522019 @default.
• W2385280152 countsByYear W23852801522020 @default.
• W2385280152 countsByYear W23852801522021 @default.
• W2385280152 countsByYear W23852801522022 @default.
• W2385280152 countsByYear W23852801522023 @default.
• W2385280152 crossrefType "journal-article" @default.
• W2385280152 hasAuthorship W2385280152A5008141462 @default.
• W2385280152 hasAuthorship W2385280152A5029938462 @default.
• W2385280152 hasAuthorship W2385280152A5038074463 @default.
• W2385280152 hasAuthorship W2385280152A5048261461 @default.
• W2385280152 hasAuthorship W2385280152A5052536282 @default.
• W2385280152 hasAuthorship W2385280152A5057530833 @default.
• W2385280152 hasAuthorship W2385280152A5062560260 @default.
• W2385280152 hasAuthorship W2385280152A5064218360 @default.
• W2385280152 hasAuthorship W2385280152A5065935445 @default.
• W2385280152 hasAuthorship W2385280152A5089856275 @default.
• W2385280152 hasBestOaLocation W23852801521 @default.
• W2385280152 hasConcept C121608353 @default.
• W2385280152 hasConcept C126322002 @default.
• W2385280152 hasConcept C134018914 @default.
• W2385280152 hasConcept C159110408 @default.
• W2385280152 hasConcept C2775883008 @default.
• W2385280152 hasConcept C2779761222 @default.
• W2385280152 hasConcept C2779951463 @default.
• W2385280152 hasConcept C2993291352 @default.
• W2385280152 hasConcept C526584372 @default.
• W2385280152 hasConcept C71315377 @default.
• W2385280152 hasConcept C71924100 @default.
• W2385280152 hasConceptScore W2385280152C121608353 @default.
• W2385280152 hasConceptScore W2385280152C126322002 @default.
• W2385280152 hasConceptScore W2385280152C134018914 @default.
• W2385280152 hasConceptScore W2385280152C159110408 @default.
• W2385280152 hasConceptScore W2385280152C2775883008 @default.
• W2385280152 hasConceptScore W2385280152C2779761222 @default.
• W2385280152 hasConceptScore W2385280152C2779951463 @default.

• next