Matches in SemOpenAlex for { <https://semopenalex.org/work/W2385323630> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W2385323630 abstract "OBJECTIVE:To observe whether the therapy of tumor necrosis factor-α(TNF-α)antagonist can influence the reactivation of hepatitis B virus(HBV)infection in inactive HBV carriers.METHODS:The medical records of 47 inactive HBV carriers who had been treated with TNF-α antagonist in outpatient department and wards of our hospital were reviewed retrospectively,and all of them had normal level of AST and ALT,positive HBsAg and HBV-DNA load posterior to the lowest detection limit(5×10~2 IU·mL~(-1))before medication.The liver function,HBV-DNA and virus serology index were observed before and after treatment.RESULTS:Reactivation of HBV occurred in 2 patients during the course of anti-TNF-α therapy.Among which 1 patient with Crohn disease returned for the fifth infusion of infliximab at 22th week,and blood test showed the reactivation of HBV infection;another patient with RA returned for the fourth infusion of infliximab at 14th week,then the reactivation of HBV infection occurred.Both patients received lamivudine and the AST and ALT levels returned to normal and HBV-DNA was lower than the lowest detection limit after 2 months.CONCLUSION:Therapy of TNF-α may influence normal liver function.The reactivation of HBV infection might happen in inactive HBV carriers whose HBV-DNA is lower than the lowest detection limit." @default.
- W2385323630 created "2016-06-24" @default.
- W2385323630 creator A5019064202 @default.
- W2385323630 date "2011-01-01" @default.
- W2385323630 modified "2023-09-25" @default.
- W2385323630 title "Clinical Observation of the Reactivation of Hepatitis B Virus Induced by Tumor Necrosis Factor-α Antagonist" @default.
- W2385323630 hasPublicationYear "2011" @default.
- W2385323630 type Work @default.
- W2385323630 sameAs 2385323630 @default.
- W2385323630 citedByCount "0" @default.
- W2385323630 crossrefType "journal-article" @default.
- W2385323630 hasAuthorship W2385323630A5019064202 @default.
- W2385323630 hasConcept C126322002 @default.
- W2385323630 hasConcept C159047783 @default.
- W2385323630 hasConcept C159654299 @default.
- W2385323630 hasConcept C17991360 @default.
- W2385323630 hasConcept C203014093 @default.
- W2385323630 hasConcept C2522874641 @default.
- W2385323630 hasConcept C2777138892 @default.
- W2385323630 hasConcept C2777382497 @default.
- W2385323630 hasConcept C2777410769 @default.
- W2385323630 hasConcept C2777869810 @default.
- W2385323630 hasConcept C2780593183 @default.
- W2385323630 hasConcept C2992208098 @default.
- W2385323630 hasConcept C45189115 @default.
- W2385323630 hasConcept C71924100 @default.
- W2385323630 hasConcept C90924648 @default.
- W2385323630 hasConceptScore W2385323630C126322002 @default.
- W2385323630 hasConceptScore W2385323630C159047783 @default.
- W2385323630 hasConceptScore W2385323630C159654299 @default.
- W2385323630 hasConceptScore W2385323630C17991360 @default.
- W2385323630 hasConceptScore W2385323630C203014093 @default.
- W2385323630 hasConceptScore W2385323630C2522874641 @default.
- W2385323630 hasConceptScore W2385323630C2777138892 @default.
- W2385323630 hasConceptScore W2385323630C2777382497 @default.
- W2385323630 hasConceptScore W2385323630C2777410769 @default.
- W2385323630 hasConceptScore W2385323630C2777869810 @default.
- W2385323630 hasConceptScore W2385323630C2780593183 @default.
- W2385323630 hasConceptScore W2385323630C2992208098 @default.
- W2385323630 hasConceptScore W2385323630C45189115 @default.
- W2385323630 hasConceptScore W2385323630C71924100 @default.
- W2385323630 hasConceptScore W2385323630C90924648 @default.
- W2385323630 hasLocation W23853236301 @default.
- W2385323630 hasOpenAccess W2385323630 @default.
- W2385323630 hasPrimaryLocation W23853236301 @default.
- W2385323630 hasRelatedWork W1536948826 @default.
- W2385323630 hasRelatedWork W1976660508 @default.
- W2385323630 hasRelatedWork W1983039036 @default.
- W2385323630 hasRelatedWork W1983059399 @default.
- W2385323630 hasRelatedWork W1988656571 @default.
- W2385323630 hasRelatedWork W2063365414 @default.
- W2385323630 hasRelatedWork W2068360666 @default.
- W2385323630 hasRelatedWork W2117577651 @default.
- W2385323630 hasRelatedWork W2147134417 @default.
- W2385323630 hasRelatedWork W2155791431 @default.
- W2385323630 hasRelatedWork W2320566544 @default.
- W2385323630 hasRelatedWork W2328410253 @default.
- W2385323630 hasRelatedWork W2329428433 @default.
- W2385323630 hasRelatedWork W2357563867 @default.
- W2385323630 hasRelatedWork W2399112941 @default.
- W2385323630 hasRelatedWork W2406005832 @default.
- W2385323630 hasRelatedWork W2410012132 @default.
- W2385323630 hasRelatedWork W2769512910 @default.
- W2385323630 hasRelatedWork W3031834989 @default.
- W2385323630 hasRelatedWork W3031853436 @default.
- W2385323630 isParatext "false" @default.
- W2385323630 isRetracted "false" @default.
- W2385323630 magId "2385323630" @default.
- W2385323630 workType "article" @default.