Matches in SemOpenAlex for { <https://semopenalex.org/work/W2385354660> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2385354660 abstract "Neferine,a bis benzyl-isoquinoline alkaloid from the seed embryo of Nelumbo nucifera Gaertn,possesses antiarrhythmic action.Its effects on the heart conducting system were investigated in the anesthetized rabbits.The sinus node recovery time and the sino-atrial conduction time were prolonged by 4 mg/kg neferine(iv,10min)from 285±40 ms and49±14 ms to 312±24 ms and 70±17 ms(p0.05),respectively.Neferine at 1-8 mg/kg iv lengthened the His-bundle electrogram A-H and H V intervals and widened V duration in a dose-dependent manner.It(8 mg/kg)prolonged the A-H and H-V intervals from 47±5 msand 17±2 ms of control to 64±3 ms(n=8,p0.01)and 26±2 ms(p0.01),respectively,widened V duration from 37±3 ms to 61±6 ms(p0.01),and also lengthened electrocardiograph P-R interval from 57±7 ms to 72±8 ms(p0.01).The effects of neferine are similar to those of quinidine.The results indicate that neferine,similar to quinidine,has an inhibitory effect on the atrioventricular and the intra-ventricular conducting systems." @default.
- W2385354660 created "2016-06-24" @default.
- W2385354660 creator A5086470272 @default.
- W2385354660 date "1990-01-01" @default.
- W2385354660 modified "2023-09-25" @default.
- W2385354660 title "Effects of neferine on the heart conduction system in anesthetized rabbits" @default.
- W2385354660 hasPublicationYear "1990" @default.
- W2385354660 type Work @default.
- W2385354660 sameAs 2385354660 @default.
- W2385354660 citedByCount "0" @default.
- W2385354660 crossrefType "journal-article" @default.
- W2385354660 hasAuthorship W2385354660A5086470272 @default.
- W2385354660 hasConcept C104397207 @default.
- W2385354660 hasConcept C126322002 @default.
- W2385354660 hasConcept C155647269 @default.
- W2385354660 hasConcept C185592680 @default.
- W2385354660 hasConcept C2776024998 @default.
- W2385354660 hasConcept C2776923262 @default.
- W2385354660 hasConcept C2779731873 @default.
- W2385354660 hasConcept C2780040984 @default.
- W2385354660 hasConcept C2780283014 @default.
- W2385354660 hasConcept C2780339425 @default.
- W2385354660 hasConcept C42219234 @default.
- W2385354660 hasConcept C71924100 @default.
- W2385354660 hasConcept C98274493 @default.
- W2385354660 hasConceptScore W2385354660C104397207 @default.
- W2385354660 hasConceptScore W2385354660C126322002 @default.
- W2385354660 hasConceptScore W2385354660C155647269 @default.
- W2385354660 hasConceptScore W2385354660C185592680 @default.
- W2385354660 hasConceptScore W2385354660C2776024998 @default.
- W2385354660 hasConceptScore W2385354660C2776923262 @default.
- W2385354660 hasConceptScore W2385354660C2779731873 @default.
- W2385354660 hasConceptScore W2385354660C2780040984 @default.
- W2385354660 hasConceptScore W2385354660C2780283014 @default.
- W2385354660 hasConceptScore W2385354660C2780339425 @default.
- W2385354660 hasConceptScore W2385354660C42219234 @default.
- W2385354660 hasConceptScore W2385354660C71924100 @default.
- W2385354660 hasConceptScore W2385354660C98274493 @default.
- W2385354660 hasLocation W23853546601 @default.
- W2385354660 hasOpenAccess W2385354660 @default.
- W2385354660 hasPrimaryLocation W23853546601 @default.
- W2385354660 hasRelatedWork W1967829561 @default.
- W2385354660 hasRelatedWork W1977493680 @default.
- W2385354660 hasRelatedWork W2037161456 @default.
- W2385354660 hasRelatedWork W2053696822 @default.
- W2385354660 hasRelatedWork W2265347483 @default.
- W2385354660 hasRelatedWork W2381115662 @default.
- W2385354660 hasRelatedWork W2404966470 @default.
- W2385354660 hasRelatedWork W2406318503 @default.
- W2385354660 hasRelatedWork W2414850154 @default.
- W2385354660 hasRelatedWork W2416352391 @default.
- W2385354660 hasRelatedWork W2416440170 @default.
- W2385354660 hasRelatedWork W2416733832 @default.
- W2385354660 hasRelatedWork W2417381977 @default.
- W2385354660 hasRelatedWork W2417728895 @default.
- W2385354660 hasRelatedWork W2418345028 @default.
- W2385354660 hasRelatedWork W2418855954 @default.
- W2385354660 hasRelatedWork W2604492658 @default.
- W2385354660 hasRelatedWork W2744048171 @default.
- W2385354660 hasRelatedWork W2751853936 @default.
- W2385354660 hasRelatedWork W3140928475 @default.
- W2385354660 isParatext "false" @default.
- W2385354660 isRetracted "false" @default.
- W2385354660 magId "2385354660" @default.
- W2385354660 workType "article" @default.