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- W2385360433 abstract "Objective To assess the specific effect and side effect of high-frequency deep brain stimulation of subthalamic nucleus(STN-DBS) and ventralis intermedius nueleus of the thalamusin(Vim-DBS) for controlling the tremor,rigidity and bradykinesia in Parkinson's disease(PD),and to study the relationship of DBS responses intraoperation with DBS effect on Parkinson's disease. Methods Three of 4 patients with PD were selected for performing STN-DBS,and the other 1 patient was performing Vim-DBS under local anesthesia. Implants were placed into STN using MRI-based stereotaxy, microelectrode recording, and intraoperative test stimulation. The effect was evaluated by the neurologist. Results Intraoperative STN stimulation strongly improved most of the parkinsonian symptoms. It was indicated that the dorsal-lateral part of STN was best position for placing lead. Dysphasia was induced if the lead was placed to deep and too lateral. Intraoperative Vim stimulation could improve shimmy and movement disorders. The lower intraoperative stimulation intensity (under 1.5 V) could result in better effect. Conclusion It is demonstrated that STN-DBS is effective for controlling cardinal symptoms of PD and Vim-DBS is effective for controlling tremor symptoms of PD." @default.
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- W2385360433 date "2006-01-01" @default.
- W2385360433 modified "2023-09-24" @default.
- W2385360433 title "Deep brain stimulation in Parkinson's disease" @default.
- W2385360433 hasPublicationYear "2006" @default.
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