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- W2385366971 abstract "Objective:To analyze the therapeutic effect and side reactions of ~(18)FDG PET/CT positioning three-dimensional conformal radiotherapy(3DCRT) for advanced prostate carcinoma.Methods:Sixty-eight cases of prostate carcinoma were randomly divided into ~(18)FDG PET/CT positioning 3DCRT group(PET/CT group)and the general CT positioning 3DCRT group(normal CT group).The location of patients in PET/CT group was determined by PET/CT and the data was transmitted to the treatment planning system(TPS),the PET image and CT image were fused together.The target volume and critical organs were determined and the treatment plan was worked out from the fused image.Then 3DCRT with conventional fraction(40Gy or so) was followed by reduced radiation field radiation to reach a total dose of 60Gy～70Gy;The location of patients in normal CT group was determined by normal CT and were treated by 3 DCRT to the same dose.Results:The average PTV volume、V_(40) of bladder and rectum of the PET/CT group were lower than that of the normal CT group(all P0.01);There was significant difference between the average PSA before and after radiotherapy(P0.01);The median recurrence time of the PET/CT group was 12.1 months,and the median recurrence time of the normal CT group was 9.2 months,there was significant difference between the two groups(P0.01);The rate of radiation reactions of gastrointestinal tract and bladder of the PET/ CT group were lower than that of normal CT group(P0.05 );The patients with GTV≤50cm~3 before theatment had better prognosis. Conclusion:PET/CT positioning 3DCRT can optimize the radiation treatment planning for advanced prostate carcinoma and reduce the radiation side reactions.The patients with early stage lesions have better prognosis than others." @default.
- W2385366971 created "2016-06-24" @default.
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- W2385366971 date "2012-01-01" @default.
- W2385366971 modified "2023-09-24" @default.
- W2385366971 title "Therapeutic Effect and Prognosis Analysis of ~(18)FDG PET/CT Positioning Three-dimensional Conformal Radiotherapy for Advanced Prostate Carcinoma" @default.
- W2385366971 hasPublicationYear "2012" @default.
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