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- W2385396496 abstract "Objective Toinvestigate the prognostic significance ofactivated mTOR(p-mTOR)expression in gastric cancer patients undergoing curative surgery.Methods The expression of p-mTOR was detected in specimens of 181 gastric cancers who underwent radical resection(R0)by immunohistochemistry.The influence of each variable on survival was analyzed by the multivariate analysis of Cox proportional hazard model.Results The positive rate of p-mTOR in gastric cancer was 51.4%.Patients with p-mTOR positive showed significantly shorter disease-free survival(DFS)and overall survival(OS)rates than those with p-mTOR-negative tumors in univariate analyses(DFS,P0.01 and OS,P0.05,respectively),and there was a trend toward a correlation between p-mTOR expression and survival in multivariate analyses(DFS,P=0.059 and OS,P=0.07,respectively). Conclusion The expression of mTOR actived is associated with poor prognosis in patients with gastric cancer underwent curative surgery." @default.
- W2385396496 created "2016-06-24" @default.
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- W2385396496 date "2009-01-01" @default.
- W2385396496 modified "2023-09-22" @default.
- W2385396496 title "Prognosis significance of p-mTOR expression in gastric cancer" @default.
- W2385396496 hasPublicationYear "2009" @default.
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