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- W2385451807 abstract "Objective To discuss the potential value of neopterin in early prognostic information of dengue virus infection.Method Neopterin concentrations were determined in serum samples from 110 severe acute dengue fever(DF) patients.The neopterin levels were compared with those in 50 respiratory syndrome measles and 40 influenza patients;155 healthy blood donors served as controls.Result In sera of acute DF patients mean neopterin concentration was 48.2 nmol/L,higher than that in patients with measles(36.3 nmol/L) and influenza(18.8 nmol/L) and in control group(6.7 nmol/L;P 0.001).In the patients with confirmed DF,an early neopterin elevation was detected on the first day after the onset of symptoms and rose to a maximum level of 54.3 nmol/L 4 days after the onset.Higher increase of neopterin level in DF patients was associated with longer duration of fever and thus predicted the clinical course of the disease.Conclusion Neopterin concentrations,showing significantly higher in DF patients than that in control group and people with other viral infections(P 0.001) and may allow early assessment of the severity of DF." @default.
- W2385451807 created "2016-06-24" @default.
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- W2385451807 date "2006-01-01" @default.
- W2385451807 modified "2023-09-28" @default.
- W2385451807 title "Detection of Serum Neopterin for Early Assessment of Dengue Virus Infection" @default.
- W2385451807 hasPublicationYear "2006" @default.
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