Matches in SemOpenAlex for { <https://semopenalex.org/work/W2385465764> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W2385465764 endingPage "40" @default.
- W2385465764 startingPage "437" @default.
- W2385465764 abstract "To investigate the effects of exhaustive exercise on contraction mediated by beta-adrenoceptor (beta-AR) in rat cardiac myocytes and to analyze the mechanism by which cardiac systolic dysfunction is caused after exhaustive exercise.Sixteen SD rats were divided randomly into sedentary group and trained group. Cardiac myocytes were isolated from sedentary group and trained group after five times of exhaustive exercise in one week. Shortening response to norepinephrine (NE), time-to-peak contraction (TTP) and time-to-95% relaxation (R95) were measured after alpha1-AR were blocked. Also shortening responses to different levels of NE were observed.Shortening amplitudes in trained rat cardiomyocytes were lower than that in sedentary group. Compared with sedentary group, shortening amplitudes induced by beta-AR stimulation were significantly decreased, meanwhile TTPs and R95 were prolonged when beta-AR were activated in trained rat cardiomyocytes. beta-AR responsiveness to NE was weakened in trained group compared with that in sedentary group.Decreased shortening cardiomyocyte systolic function stimulating by beta-AR could result in cardiac systolic dysfunction after exhaustive exercise." @default.
- W2385465764 created "2016-06-24" @default.
- W2385465764 creator A5002096365 @default.
- W2385465764 creator A5032909562 @default.
- W2385465764 creator A5069425198 @default.
- W2385465764 date "2013-09-01" @default.
- W2385465764 modified "2023-09-23" @default.
- W2385465764 title "[Effects of exhaustive exercise on contractile responses mediated by beta-adrenoceptor in rat cardiac myocytes]." @default.
- W2385465764 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24386822" @default.
- W2385465764 hasPublicationYear "2013" @default.
- W2385465764 type Work @default.
- W2385465764 sameAs 2385465764 @default.
- W2385465764 citedByCount "0" @default.
- W2385465764 crossrefType "journal-article" @default.
- W2385465764 hasAuthorship W2385465764A5002096365 @default.
- W2385465764 hasAuthorship W2385465764A5032909562 @default.
- W2385465764 hasAuthorship W2385465764A5069425198 @default.
- W2385465764 hasConcept C111566952 @default.
- W2385465764 hasConcept C126322002 @default.
- W2385465764 hasConcept C134018914 @default.
- W2385465764 hasConcept C163415756 @default.
- W2385465764 hasConcept C164705383 @default.
- W2385465764 hasConcept C199360897 @default.
- W2385465764 hasConcept C207200792 @default.
- W2385465764 hasConcept C24998067 @default.
- W2385465764 hasConcept C2776174256 @default.
- W2385465764 hasConcept C2778198053 @default.
- W2385465764 hasConcept C41008148 @default.
- W2385465764 hasConcept C71924100 @default.
- W2385465764 hasConceptScore W2385465764C111566952 @default.
- W2385465764 hasConceptScore W2385465764C126322002 @default.
- W2385465764 hasConceptScore W2385465764C134018914 @default.
- W2385465764 hasConceptScore W2385465764C163415756 @default.
- W2385465764 hasConceptScore W2385465764C164705383 @default.
- W2385465764 hasConceptScore W2385465764C199360897 @default.
- W2385465764 hasConceptScore W2385465764C207200792 @default.
- W2385465764 hasConceptScore W2385465764C24998067 @default.
- W2385465764 hasConceptScore W2385465764C2776174256 @default.
- W2385465764 hasConceptScore W2385465764C2778198053 @default.
- W2385465764 hasConceptScore W2385465764C41008148 @default.
- W2385465764 hasConceptScore W2385465764C71924100 @default.
- W2385465764 hasIssue "5" @default.
- W2385465764 hasLocation W23854657641 @default.
- W2385465764 hasOpenAccess W2385465764 @default.
- W2385465764 hasPrimaryLocation W23854657641 @default.
- W2385465764 hasRelatedWork W2005645041 @default.
- W2385465764 hasRelatedWork W2057285056 @default.
- W2385465764 hasRelatedWork W2065988110 @default.
- W2385465764 hasRelatedWork W2083733396 @default.
- W2385465764 hasRelatedWork W2133836273 @default.
- W2385465764 hasRelatedWork W2144650168 @default.
- W2385465764 hasRelatedWork W2145930882 @default.
- W2385465764 hasRelatedWork W2153348972 @default.
- W2385465764 hasRelatedWork W2374754314 @default.
- W2385465764 hasRelatedWork W3160140598 @default.
- W2385465764 hasVolume "29" @default.
- W2385465764 isParatext "false" @default.
- W2385465764 isRetracted "false" @default.
- W2385465764 magId "2385465764" @default.
- W2385465764 workType "article" @default.