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- W2385496866 abstract "AIM:To investigate the secretion mode of hepatocyte growth factor/scatter factor(HGF/SF) by gingival fibroblasts in vitro . METHODS: Gingival fibroblasts were cultured, and the fibroblast populated collagen lattices (FPCLs) were farbricatad and divided into 3 groups. The diameter of the FPCL was measured from day 0 to day 7, and the degree of cell-mediated reorganization was estimated with three separate lattice diameter measurements. RESULTS: No differences in the initial rate of lattice reorganization were observed between fibroblasts in serum-free median with and without 20 (or 40)ng/ml rHGF groups ( P 0.05) ;culture in the presence of serum significantly stimulated lattice reorganization( P 0.01). CONCLUSION: rHGF does not modulate fibroblast-mediated extracellular matrix reorganization. This study does not provide the evidence for the autocrine of HGF/SF by gingival fibroblasts. [" @default.
- W2385496866 created "2016-06-24" @default.
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- W2385496866 date "2000-01-01" @default.
- W2385496866 modified "2023-09-25" @default.
- W2385496866 title "An investigation to the secretion mode of Hepatocyte Growth Factor/Scatter Factor by gingival fibroblasts in vitro" @default.
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