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- W2385511930 abstract "In order to research the effect of PGE, on hepatic regeneration aftr partial hepatectomy. We examined the index of 3H thymidine incoporated into the DNA of hepatic cells and TGF-α(trans-forming growth factor-α) mRNA expression. Forty rats were divided into five groups at random. Each group has eight rats. Group 1 (control group),in which 70% liver was hepatectomized was injected with normal solution intraperitoneally before operation; Group 2 was injected Intraperltoneally with PGE2 30 minut before 70% hepatectomy ; Group 3 was injected intraperitoneally with PGE2 30 minutes after 70% hepatectomy; Group 4 was injected with PGE212 hours after 70% hepatectomy (Group 5 pretend hepatectomy. The index of 3H-thymidine incorporated into DNA of hepatic cells in group 2 was 1. 5 times higher than control group(P0. 01). Group 3 and 4 were as high as control group. Group 5 was almost equal zero. The level of TGFα mRNA in group 2 was higher than that of groupl, 3,4. Normal rat liver has no TGF-α mRNA." @default.
- W2385511930 created "2016-06-24" @default.
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- W2385511930 date "1992-01-01" @default.
- W2385511930 modified "2023-09-25" @default.
- W2385511930 title "THE EFFECT OF PGE_2 ON HEPATIC REGENERATION AFTERPARTIAL HEPATECTOMY AND EXPRESSION OF TGF-α mRNA IN THE PROCESS OF HEPATIC CELL REGENERATION" @default.
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