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- W2385538760 abstract "Objective: To investigate the clinicopathological significance of the expression of thymosin β10 (Tβ10) in esophageal carcinoma. Methods: Immunohistochemical staining was used to detect the expression of Tβ10 in 70 cases of esophageal carcinoma and 30 cases of para-cancerous normal esophageal mucosa. The results in combination with common clinicopathological parameters were analyzed. Results: The positive expression rate of Tβ10 was significantly higher in esophageal carcinoma (75.71%) than that in para-cancerous normal esophageal mucosa (23.33%, P 0.01). The positive expression rate of Tβ10 was significantly lower in well differentiated esophageal carcinoma than that in moderate or poor differentiated carcinoma. The positive expression rate of Tβ10 was significantly lower in mucosa or sub-mucosa of esophageal carcinoma than that in muscularis propria of carcinoma (P 0.05). The positive expression rate of Tβ10 was significantly lower in esophageal carcinoma without lymph node metastasis than that of esophageal carcinoma with lymph node metastasis (P 0.05). Conclusion: Tβ10 was highly expressed in esophageal carcinoma, which was correlated with the differentiation, invasion and metastasis. Tβ10 might be a new tumor marker for diagnosis of human esophageal carcinoma." @default.
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- W2385538760 date "2010-01-01" @default.
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- W2385538760 title "Clinicopathological Significance of the Expression of Thymosin p10 Protein in Esophageal Carcinoma" @default.
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