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- W2385655553 abstract "Heat shock proteins(HSPs)existed in various organisms as a conserved protein family.HSPs play important physiological functions in cell apoptosis and influence multiple components of the apoptotic pathways,such as to maintain cell survival by inhibiting the apoptotic cascades or to accelerate cell apoptosis as the chaperons of certain apoptotic factors.HSP70 and mitochondrial Hsp60 activate DNase and promote caspase-dependent apoptosis.In this review,we focus on the role of HSP90,HSP70,HSP60 and other small HSPs to summarize the interactions of HSPs with the components of the apoptotic pathways,and discuss their potentials for the regulation of the apoptotic signal networks." @default.
- W2385655553 created "2016-06-24" @default.
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- W2385655553 date "2011-01-01" @default.
- W2385655553 modified "2023-09-25" @default.
- W2385655553 title "Regulation of Apoptosis Signaling Pathway by Common Heat Shock Proteins" @default.
- W2385655553 hasPublicationYear "2011" @default.
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