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- W2385718596 abstract "Objective: To investigate the effects of VEGF, VEGFR and MMP-9 in the invasion and metastasis of epithelial ovarian cancer. Methods: The levels of VEGF, VEGFR and MMP-9 were tested by immunohistochemical technology. The expressions of VEGF and MMP-9 were measured by Wilcoxon test and Spearman analysis. Survival curves were analyzed by Kaplan-Meier method. Results: VEGF was expressed in tumor cell plasm of epithelial ovarian cancer. VEGF expression increased in the conditions of ovarian cancer late stage, bad differentiation, amount of ascitic volume and more remnant neoplasm. VEGFR was expressed in plasm of ovarian cancer endothelial cells, especially in the endothelial cells near to carcinoma nests. MMP-9 was expressed in interstitial cells. MMP-9 expression increased in late stage and bad differentiation patients. VEGF was positive correlated with MMP-9 in epithelial ovarian cancer. Conclusion: VEGF and MMP-9 cooperate with each other in neovascularization, invasion and metastasis." @default.
- W2385718596 created "2016-06-24" @default.
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- W2385718596 date "2006-01-01" @default.
- W2385718596 modified "2023-09-28" @default.
- W2385718596 title "Study on the Expressions of Vascular Endothelial Growth Factor and Its Receptors and Matrix Metalloproteinase 9 in Epithelial Ovarian Cancer" @default.
- W2385718596 hasPublicationYear "2006" @default.
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