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- W2385728568 abstract "Objective To investigate the hemorheological changes in type 2 diabetic patients with coronary heart disease and the effect of prostaglandin E1 on those changes.Methods We measured the hemorheological parameters in 53 type 2 diabetic patients with coronary heart disease and 33 patients with type 2 diabetes mellitus alone.The data were compared with those from the control group.The patients with type 2 diabetes mellitus and coronary heart disease were administered with prostaglandin E1 and their hemorheological changes were observed.Results Whole blood viscosity,plasma viscosity,plasma fibrinogen,erythrocyte aggregation index,and platelet aggregation rate were significantly elevated while erythrocyte deformability was markedly decreased in the type 2 diabetic patients,and more evidently in those with coronary heart disease(P 0.05),as compared with those in the control group.A noticeable decrease in blood viscosity and platelet aggregation rate occurred in the type 2 diabetic patients with coronary heart disease receiving prostaglandin E1(P 0.05).Conclusions Blood viscosity and platele aggregation ability are significantly elevated in type 2 diabetic patients with coronary heart disease.Prostaglandin E1 may improve the hemorheology and microcirculation in those patients." @default.
- W2385728568 created "2016-06-24" @default.
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- W2385728568 date "2006-01-01" @default.
- W2385728568 modified "2023-09-26" @default.
- W2385728568 title "Effect of prostaglandin E_1 on hemorheology in type 2 diabetic patients with coronary heart disease" @default.
- W2385728568 hasPublicationYear "2006" @default.
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