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- W2385760688 abstract "Objective To investigate the association between interleukin-8(IL-8)-251A/T polymorphism and cervical cancer.Methods The polymorphism of IL-8-251A/T were analyzed in 219 patients with cervical cancer(cervical cancer group) and 295 healthy person(control group) by polymerase chain reaction restriction fragment length polymorphism.Results The genetypes of TT,AT and AA were present in both cervical cancer group and control group for IL-8-251A/T gene polymorphism.The frequency of each genetype was 31.1%(TT),49.3%(AT) and 19.6%(AA),and frequency of each allele was 44.3%(A) and 55.7%(T) in cervical cancer group.The frequency of each genetype was 42.7%(TT),45.1%(AT) and 12.2%(AA),and frequency of each allele was 34.7%(A) and 65.3%(T) in control group.There were significant differences in genetype and allele frequencies of the IL-8-251A/T polymorphism between two groups(χ2=0.953,572.428;P=0.009,0.000).Conclusion IL-8-251A/T polymorphism may be associated with cervical cancer." @default.
- W2385760688 created "2016-06-24" @default.
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- W2385760688 date "2011-01-01" @default.
- W2385760688 modified "2023-10-11" @default.
- W2385760688 title "Association between-251A/T polymorphism of interleukin-8 gene and cervical cancer" @default.
- W2385760688 hasPublicationYear "2011" @default.
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