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- W2385799244 abstract "【Objective】 To investigate the relationship between 5HT2A receptor and 5-HT transporter promoter polymorphisms(5-HTTLPR) and attention deficit hyperactivity disorder(ADHD) with and without impulsivity. 【Methods】 147 children with ADHD in Hunan area were involved,and their parents complete Barratt Impulsiveness Scale 11th version(BIS-11).Subjiects were divided into two groups,72 children whose total score of BIS-11 ≥cut-off point composed the impulsivity group,while 75 children's score that composed non-impulsivity group.The genotype and alleles were examined with polymerase chain reaction(PCR),nondenaturing polyacrylamide gel electrophoresis and silver staining. 【Results】 There were also no significant differences in the frequency of 5-HT2A receptor T102C between impulsivity and nonimpulsivity group.There were also no significant differences in the frequencies of the genotypes and alleles of 5-HTTLPR between ADHD with and without impulsivity. 【Conclusion】 There is no association between ADHD with and without impulsivity and 5-HT2A receptor T102C,5-HTTLPR in this Chinese sample." @default.
- W2385799244 created "2016-06-24" @default.
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- W2385799244 date "2007-01-01" @default.
- W2385799244 modified "2023-09-23" @default.
- W2385799244 title "Association of 5-HT2A receptor and 5-HT transporter promoter gene polymorphism and attention deficit hyperactivity disorder with and without impulsivity" @default.
- W2385799244 hasPublicationYear "2007" @default.
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