Matches in SemOpenAlex for { <https://semopenalex.org/work/W2385812710> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2385812710 abstract "The objective of this study is to investigate the relationship between pathological lesion and transcription,expression and distribution of heat shock protein 60(HSP60) in kidney of chickens infected by Marek's disease virus(MDV).Tumor animal model was successfully established by infecting 1 day old chickens with MDV.Real-time RT-PCR,histopathological,immunohistochemistrical methods were used to detect the pathological lesion,transcription level,expression level and distribution of HSP60 in the kidney.After 21 days post-infection(PI),obvious pathological damage appeared in the kidneys of chickens infected by MDV.HSP60 was mainly distributed in the cytoplasm of the oncocyte and interstitial macrophages in the tumor regions.Within the course of MD,the contents of HSP60 of effected group were always higher than blank control group and vaccine control group,which was significantly higher after 28 days,and the mostly was about 8.608 and 12.752 times at the age of 28 days.The tendency changes looked like a downward parabola,during 7 to 21-day-old,the level of HSP60 mRNA transcription of effected group was in the rising stage,and then gradually dropped.When 21-day-old the maximum was came on,which was about 1.222 and 1.179 times of two control groups.Throughout all stages the level of transcription was higher than blank control group,and during 14 to 28-day-old was significantly higher(P0.01).The MDV infection caused resistance to infection and antitumor response in the progress of MD,the stress related kidney damage resulted in the over-expression of HSP60 in tumor lesions and surrounding tissues.A corresponding increase came to the mRNA transcription level of it in kidney tissues.The rapid expression changes of HSP60 was basic consistent with its mRNA transportation level,but not completely linear.And they were closely related with the onset and progression of tumors,which might be hallmarks to diagnose and determine the process of tumor caused by MDV." @default.
- W2385812710 created "2016-06-24" @default.
- W2385812710 creator A5054688353 @default.
- W2385812710 date "2013-01-01" @default.
- W2385812710 modified "2023-09-23" @default.
- W2385812710 title "Relationship between Expression of HSP60 and Tumor Lesion of Chickens Kidney in Progress of MD" @default.
- W2385812710 hasPublicationYear "2013" @default.
- W2385812710 type Work @default.
- W2385812710 sameAs 2385812710 @default.
- W2385812710 citedByCount "0" @default.
- W2385812710 crossrefType "journal-article" @default.
- W2385812710 hasAuthorship W2385812710A5054688353 @default.
- W2385812710 hasConcept C104317684 @default.
- W2385812710 hasConcept C105580179 @default.
- W2385812710 hasConcept C134018914 @default.
- W2385812710 hasConcept C138885662 @default.
- W2385812710 hasConcept C142724271 @default.
- W2385812710 hasConcept C146621620 @default.
- W2385812710 hasConcept C16685009 @default.
- W2385812710 hasConcept C179926584 @default.
- W2385812710 hasConcept C203014093 @default.
- W2385812710 hasConcept C205260736 @default.
- W2385812710 hasConcept C207886595 @default.
- W2385812710 hasConcept C2780091579 @default.
- W2385812710 hasConcept C2780931953 @default.
- W2385812710 hasConcept C2781156865 @default.
- W2385812710 hasConcept C41895202 @default.
- W2385812710 hasConcept C54355233 @default.
- W2385812710 hasConcept C68991219 @default.
- W2385812710 hasConcept C71924100 @default.
- W2385812710 hasConcept C86803240 @default.
- W2385812710 hasConceptScore W2385812710C104317684 @default.
- W2385812710 hasConceptScore W2385812710C105580179 @default.
- W2385812710 hasConceptScore W2385812710C134018914 @default.
- W2385812710 hasConceptScore W2385812710C138885662 @default.
- W2385812710 hasConceptScore W2385812710C142724271 @default.
- W2385812710 hasConceptScore W2385812710C146621620 @default.
- W2385812710 hasConceptScore W2385812710C16685009 @default.
- W2385812710 hasConceptScore W2385812710C179926584 @default.
- W2385812710 hasConceptScore W2385812710C203014093 @default.
- W2385812710 hasConceptScore W2385812710C205260736 @default.
- W2385812710 hasConceptScore W2385812710C207886595 @default.
- W2385812710 hasConceptScore W2385812710C2780091579 @default.
- W2385812710 hasConceptScore W2385812710C2780931953 @default.
- W2385812710 hasConceptScore W2385812710C2781156865 @default.
- W2385812710 hasConceptScore W2385812710C41895202 @default.
- W2385812710 hasConceptScore W2385812710C54355233 @default.
- W2385812710 hasConceptScore W2385812710C68991219 @default.
- W2385812710 hasConceptScore W2385812710C71924100 @default.
- W2385812710 hasConceptScore W2385812710C86803240 @default.
- W2385812710 hasLocation W23858127101 @default.
- W2385812710 hasOpenAccess W2385812710 @default.
- W2385812710 hasPrimaryLocation W23858127101 @default.
- W2385812710 hasRelatedWork W111700594 @default.
- W2385812710 hasRelatedWork W1483312856 @default.
- W2385812710 hasRelatedWork W1950574328 @default.
- W2385812710 hasRelatedWork W2064338748 @default.
- W2385812710 hasRelatedWork W2072104087 @default.
- W2385812710 hasRelatedWork W2088232965 @default.
- W2385812710 hasRelatedWork W2315163354 @default.
- W2385812710 hasRelatedWork W2317862320 @default.
- W2385812710 hasRelatedWork W2334844291 @default.
- W2385812710 hasRelatedWork W2349751593 @default.
- W2385812710 hasRelatedWork W2350396238 @default.
- W2385812710 hasRelatedWork W2361330435 @default.
- W2385812710 hasRelatedWork W2371680741 @default.
- W2385812710 hasRelatedWork W2386335196 @default.
- W2385812710 hasRelatedWork W2470289230 @default.
- W2385812710 hasRelatedWork W2508727713 @default.
- W2385812710 hasRelatedWork W2570762666 @default.
- W2385812710 hasRelatedWork W3030502480 @default.
- W2385812710 hasRelatedWork W3031278325 @default.
- W2385812710 hasRelatedWork W2805188004 @default.
- W2385812710 isParatext "false" @default.
- W2385812710 isRetracted "false" @default.
- W2385812710 magId "2385812710" @default.
- W2385812710 workType "article" @default.