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- W2385858987 abstract "Objective:To discuss the value of ELISA to detect the application of peripheral blood COX-2 activity on subclinical coronary atherosclerosis.Methods:Used selective COX-2 inhibitors (celecoxib) to perform short-term intervention on sub-clinical coronary atherosclerosis and detected different groups of plasma COX-2 by ELISA and analyzed with clinical data.Results:The level of subclinical coronary AS group was [(10.84±3.11)U/L],which was obviously higher than that of the normal comparison group[(6.97±1.25)U/L];The difference between celecoxib group and placebo group was significant (P0.05);and the level of COX-2 obviously reduced after receiving celecoxib,no difference compared with the normal group(P0.05).Conclusion:COX-2 level is significantly associated with subclinical coronary atherosclerosis(AS),and detecting the activity of plasma COX-2 by ELISA can be used as diagnosis of subclinical coronary atherosclerosis and a reference indicator to prognostic." @default.
- W2385858987 created "2016-06-24" @default.
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- W2385858987 date "2011-01-01" @default.
- W2385858987 modified "2023-09-24" @default.
- W2385858987 title "The application discussion of ELISA to detect PB COX-2 activity on subclinical coronary atherosclerosis" @default.
- W2385858987 hasPublicationYear "2011" @default.
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