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- W2385859688 abstract "Objective: To study the effects of Jiangtangbaoshenfang to early diabetic nephropathy in oxidative stress and to explore the treating mechanism of Jiangtangbaoshenfang to early diabetic nephropathy. Methods: 72 patients who met the inclusion criteria were randomly divided into western medicine group (X group) and traditional chinese medicine group (Z group). The patients of X group were given oral irbesartan 150 mg per time, one time per day, the patients at Z group were given oral Jiangtangbaoshenfang 2 did per day. The changes of the blood glucose, proteinuria, serum ultra-dismutase (SOD), catalase (CAT), malondialdehyde (MDA) were analyzed before and after 8 weeks treatment. Results: After 8 weeks, Jiangtangbaoshenfang significantly decreased fasting blood glucose to (8.4±1.0) mmol/L, decreased 2 hour postprandial blood glucose to (12.1±1.4) mmol/L, decreased HbA1c to (8.0±0.3)%, decreased 24 hour urine protein to (185.6±17.7) mg, decreased 24 hour urinary albumin excretion rate to (54.2±7.9) μg/min and MDA to (5.1±0.4) nmol/ml (P0.05); and significantly increased SOD to (80.0±8.7) nU/ml and CAT to (26.4±2.4) nU/ml (P0.05). Conclusion: Jiangtangbaoshenfang can protect diabetic nephropathy by inhibiting oxidative stress." @default.
- W2385859688 created "2016-06-24" @default.
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- W2385859688 date "2011-01-01" @default.
- W2385859688 modified "2023-09-23" @default.
- W2385859688 title "The effects of Jiangtangbaoshenfang to patients with early diabetic nephropathy in oxidative stress" @default.
- W2385859688 hasPublicationYear "2011" @default.
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