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- W2385900536 abstract "CpG islands of human genome,located mainly in the promoter as well as the first extron regions,are GC rich short stretches(100～1 000 bp) and they link with 60% of human coding genes.Methylation of CpG sites in the promoter regions of genes can lead to decreased expression and silencing of the tumor suppressor genes and contribute to oncogenesis.Recently,DNA methylation has become one of epigenetics research hot spots.The research development of DNA methylation in colorectal carcinoma was reviewed in this article." @default.
- W2385900536 created "2016-06-24" @default.
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- W2385900536 date "2009-01-01" @default.
- W2385900536 modified "2023-09-25" @default.
- W2385900536 title "DNA Methylation in Colorectal Carcinoma" @default.
- W2385900536 hasPublicationYear "2009" @default.
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