Matches in SemOpenAlex for { <https://semopenalex.org/work/W2385920171> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2385920171 endingPage "6" @default.
- W2385920171 startingPage "93" @default.
- W2385920171 abstract "Adhesion to extracellular matrix plays important roles in the regulation of survival, proliferation, differentiation and homing of hematopoietic cells and is regulated by a wide variety of growth factors, adhesion receptors and other ligands that mediate the cell to matrix and cell to cell interaction. Stem cell factor (SCF) plays important roles in the regulating growth and self-renewal of hematopoietic stem/progenitor cells. In the report, the effects of stem cell factor on the adhesion of hematopoietic cells to fibronectin were observed by using a hematopoietic growth factor dependent cell line-Mo7e. Results showed that Mo7e cells express the very late antigen VLA-4 (beta1 alpha4) and VLA-5 (beta1 alpha5) integrins. The expression of the SCF receptor (c-kit) was also detected in the Mo7e cells. SCF enhances the adhesion of Mo7e cells to fibronectin in a concentration dependent manner. SCF enhanced adhesion of Mo7e cells to fibronectin was blocked by anti-beta1, alpha4 and alpha5 antibodies. Addition of PI-3 kinase inhibitors also blocked the adhesion of Mo7e cells to fibronectin induced by SCF. It was concluded that SCF enhances the adhesion of Mo7e cells to fibronectin, and this process is mediated by integrins and PI-3 kinase pathway." @default.
- W2385920171 created "2016-06-24" @default.
- W2385920171 creator A5018764399 @default.
- W2385920171 creator A5045442544 @default.
- W2385920171 creator A5055070776 @default.
- W2385920171 creator A5056204035 @default.
- W2385920171 creator A5059509650 @default.
- W2385920171 date "2002-04-01" @default.
- W2385920171 modified "2023-09-24" @default.
- W2385920171 title "[Stem cell factor enhances the adhesion of hematopoietic cells to fibronectin]." @default.
- W2385920171 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12513805" @default.
- W2385920171 hasPublicationYear "2002" @default.
- W2385920171 type Work @default.
- W2385920171 sameAs 2385920171 @default.
- W2385920171 citedByCount "0" @default.
- W2385920171 crossrefType "journal-article" @default.
- W2385920171 hasAuthorship W2385920171A5018764399 @default.
- W2385920171 hasAuthorship W2385920171A5045442544 @default.
- W2385920171 hasAuthorship W2385920171A5055070776 @default.
- W2385920171 hasAuthorship W2385920171A5056204035 @default.
- W2385920171 hasAuthorship W2385920171A5059509650 @default.
- W2385920171 hasConcept C109159458 @default.
- W2385920171 hasConcept C122871604 @default.
- W2385920171 hasConcept C1491633281 @default.
- W2385920171 hasConcept C16224149 @default.
- W2385920171 hasConcept C170493617 @default.
- W2385920171 hasConcept C178790620 @default.
- W2385920171 hasConcept C185592680 @default.
- W2385920171 hasConcept C189165786 @default.
- W2385920171 hasConcept C195687474 @default.
- W2385920171 hasConcept C2022786 @default.
- W2385920171 hasConcept C2775960820 @default.
- W2385920171 hasConcept C28328180 @default.
- W2385920171 hasConcept C55493867 @default.
- W2385920171 hasConcept C84416704 @default.
- W2385920171 hasConcept C85789140 @default.
- W2385920171 hasConcept C86492073 @default.
- W2385920171 hasConcept C86803240 @default.
- W2385920171 hasConcept C95444343 @default.
- W2385920171 hasConceptScore W2385920171C109159458 @default.
- W2385920171 hasConceptScore W2385920171C122871604 @default.
- W2385920171 hasConceptScore W2385920171C1491633281 @default.
- W2385920171 hasConceptScore W2385920171C16224149 @default.
- W2385920171 hasConceptScore W2385920171C170493617 @default.
- W2385920171 hasConceptScore W2385920171C178790620 @default.
- W2385920171 hasConceptScore W2385920171C185592680 @default.
- W2385920171 hasConceptScore W2385920171C189165786 @default.
- W2385920171 hasConceptScore W2385920171C195687474 @default.
- W2385920171 hasConceptScore W2385920171C2022786 @default.
- W2385920171 hasConceptScore W2385920171C2775960820 @default.
- W2385920171 hasConceptScore W2385920171C28328180 @default.
- W2385920171 hasConceptScore W2385920171C55493867 @default.
- W2385920171 hasConceptScore W2385920171C84416704 @default.
- W2385920171 hasConceptScore W2385920171C85789140 @default.
- W2385920171 hasConceptScore W2385920171C86492073 @default.
- W2385920171 hasConceptScore W2385920171C86803240 @default.
- W2385920171 hasConceptScore W2385920171C95444343 @default.
- W2385920171 hasIssue "2" @default.
- W2385920171 hasLocation W23859201711 @default.
- W2385920171 hasOpenAccess W2385920171 @default.
- W2385920171 hasPrimaryLocation W23859201711 @default.
- W2385920171 hasRelatedWork W1974956317 @default.
- W2385920171 hasRelatedWork W1991995593 @default.
- W2385920171 hasRelatedWork W1996296303 @default.
- W2385920171 hasRelatedWork W2093334921 @default.
- W2385920171 hasRelatedWork W2118300139 @default.
- W2385920171 hasRelatedWork W2124854149 @default.
- W2385920171 hasRelatedWork W2150662590 @default.
- W2385920171 hasRelatedWork W2385920171 @default.
- W2385920171 hasRelatedWork W2411839509 @default.
- W2385920171 hasRelatedWork W88478485 @default.
- W2385920171 hasVolume "10" @default.
- W2385920171 isParatext "false" @default.
- W2385920171 isRetracted "false" @default.
- W2385920171 magId "2385920171" @default.
- W2385920171 workType "article" @default.