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- W2385963534 abstract "Objective To compare the efficacy and safety of budesonide/formoterol dry powder inhaler(with salbutamol/budesonide aerosol combination therapy in the treatment of moderate-to-severe persistent asthma.Methods In this open,randomized,parallel-group trial,80 patients with moderate-to-severe persistent asthma,aged from 18 to 70 years,were randomizely divided into study group and control group.The study group of 43 patients received budesonide/formoterol(symbicort turbuhaler) 160 μg/4.5 μg/per inhalation twice a day via inhaler.The control group of 37 patients received budesonide 200 μg/inhalation twice a day and salbutamol aerosol 100 μg/inhalation four times a day.Clinical symptoms,pulmonary function and adverse event profiles were examined.Results Relief in asthma symptoms and rescue medication use were observed in the two groups.Improvement in symbicort turbuhaler group occurred earlier than the control group(P0.05).Forced expiratory volume in 1s(FEV1) increased in both groups,but there was no difference between the two groups.The morning peak expiratory flow(PEFam) and the evening peak expiratory flow(PEFpm) increased significantly in the symbicort turbuhaler as compared to the control group(P0.05).Conclusion Budesonide/formterol dry powder inhaler provides more rapid relief and convenience when compared to the combination use of pulmicort turbuhaler and salbutamol,although both groups have good efficacy and safety." @default.
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- W2385963534 date "2009-01-01" @default.
- W2385963534 modified "2023-09-28" @default.
- W2385963534 title "Efficacy of budesonide/formoterol dry powder inhaler in the management of adult asthma." @default.
- W2385963534 hasPublicationYear "2009" @default.
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