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- W2385977656 abstract "Objective To explore the hereditary susceptibility of HLA-DRB1 and-DQB1 alleles of epidemic hemorrhagic fever(EHF) at gene level and to further the features of their immunogenetics.Methods The polymorphisms of HLA-DRB1 and-DQB1 alleles were typed by sequence specific primer based on polymerase chain reaction in 50 patients with EHF and 50 normal control subjects.Results The allele frequency of HLA-DRB116 allele was significantly higher in patients than that in normal controls(Pc=0.010 6).There was no significantly difference between the rested alleles of HLA-DRB1 and-DQB1 in two groups(Pc0.05).Conclusions HLA-DRB116 allele was initially be determined predisposing gene of EHF." @default.
- W2385977656 created "2016-06-24" @default.
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- W2385977656 date "2009-01-01" @default.
- W2385977656 modified "2023-09-24" @default.
- W2385977656 title "Association of HLA-DRB1,-DQB1 alleles with epidemic hemorrhagic fever" @default.
- W2385977656 hasPublicationYear "2009" @default.
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