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- W2386021947 abstract "Objective To study the polymorphism of HLA haplotype in Hunan population. Methods The HLA-A,B,DR low genotyping(n=3 664) were detected by the polymerase chain reaction with sequence specific primer technique. The haplotype frequencies of HLA-AB,HLA-BDR,HLA-ABDR were obtained by the square-root method,And the data of Hunan population were compared with other populations.Results 350 HLA-AB haplotypes,408 HLA-BDR haplotypes and 1935 HLA-ABDR haplotypes were detected.Among them,36 HLA-AB haplotypes and 48 HLA-BDR haplotypes were in strongest linkage disequilibrium. The most common haplotypes were A2-B46,A11-B60,A24-B60,B46-DR9,B60-DR15,B60-DR4,A2-B46-DR9,A33-B58-DR3,A11-B75-DR12,respectively.Conclusion The polymorphism of HLA haplotype of Hunan population is multiple. The HLA haplotype distribution of Hunan population is similar to Han population in South China,but it has its own characteristics." @default.
- W2386021947 created "2016-06-24" @default.
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- W2386021947 date "2006-01-01" @default.
- W2386021947 modified "2023-09-23" @default.
- W2386021947 title "Study of Characterization of Polymorphyism of the HLA Haplotype in Hunan Distirct Population" @default.
- W2386021947 hasPublicationYear "2006" @default.
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