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- W2386021978 abstract "Objective: To investigate the expressions and their significance of p27,β-catenin,p21-ras in breast benign and maligant lesions.Methods: Immunohistochemical staining method of Envision was used to detect the p27,β-catenin and p21-ras gene expressions in 15 usual ductal hyperplasia,28 atypical ductal hyperplasia and 25 breast cancer tissues.Results: Immunohistochemical staining method of Envision results revealed that when compared with the p27 and β-catenin positive rates of breast cancer(36.0% and 84.0%,respectively) the p27 and β-catenin positive rates of atypical ductal hyperplasia(82.1% and 28.5%,respectively) were significantly lower(P0.05).The p21-ras positive rates was 13.3%(2/15),32.1%(9/28),68.0%(17/25) in usual ductal hyperplasia,atypical ductal hyperplasia and breast cancer respectively.The positive rates of p21-ras in breast benign and maligant lesions was significant(P0.05).Conclusion: It is suggested that the abnormal expressions of p27,β-catenin and p21-ras may play roles in the pathogenesis of breast carcinoma." @default.
- W2386021978 created "2016-06-24" @default.
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- W2386021978 date "2007-01-01" @default.
- W2386021978 modified "2023-09-26" @default.
- W2386021978 title "The expression and significance of p27,β-catenin,p21-ras in breast benign and maligant lesions" @default.
- W2386021978 hasPublicationYear "2007" @default.
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