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- W2386022721 abstract "Objective To study the effects of complex prescription with the effects of replenishing qi,activating blood and resolving phlegm on the levels of IL-8 and TNF-α in BALF(bronchio-alveolar lavage fluid) and the changes of the hemorheology of the pulmonary fibrosis model rats.Methods The rat model of pulmonary fibrosis was induced by Pingyangmycin(bleomycin);the changes of some indexes in every group(blank group,model group,Chinese drug group I and Chinese drug group II) were observed on 28th day after the treatment.Results The levels of IL-8 and TNF-α in BALF,blood viscosity,plasma viscosity and platelet aggregation rate were increased;the erythrocyte deformability decreased obviously in the model group(P0.01 or P0.05).In the Chinese drug groups,the levels of IL-8 and TNF-α in BALF,blood viscosity,plasma viscosity and platelet aggregation rate decreased,the erythrocyte deformability increased(P0.05),and the effect of Chinese drug II was more significant than that of Chinese drug II.Conclusion The complex prescription with the effects of replenishing qi,activating blood and resolving phlegm has marked preventive and therapeutic effect on pathological process in rats with pingyangmycin(bleomycin) induced pulmonary fibrosis." @default.
- W2386022721 created "2016-06-24" @default.
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- W2386022721 date "2007-01-01" @default.
- W2386022721 modified "2023-09-24" @default.
- W2386022721 title "Effect of complex prescriptions for replenishing qi,activating blood and resolving phlegm on levels of IL-8 and TNF-α in BALF and on hemorheology in rats with pulmonary fibrosis" @default.
- W2386022721 hasPublicationYear "2007" @default.
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