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- W2386060632 abstract "Objective To research the effects ofQingfei Kangfu Mixtureon hormone-dependent dermatitis in guinea pig models.Methods Fifty guinea pigs(25 female,25 male) were randomized into five groups:control group,model group,small dose and large dose groups ofQingfei Kangfu Mixtureand positive group.The 0.05% clobetasol propionate tincture was used to establish the models and corresponding measures to intervene the models for 28 days.The skin lesions,pathologic changes and IgE in serum were observed before and after experiment.Results Compared with that of in control group,the skin lesions were obvious and the IgE had increased in the other groups,with significant difference(P0.05,P0.01),it showed the successful models had established.The skin lesions were improved and IgE levels were decreased after treatment inQingfei Kangfu Mixturegroups,there was significant difference between model group and Qingfei Kangfu Mixturegroups(P 0.05);in large dose group ofQingfei Kangfu Mixture,the level of IgE was decreased significantly,and the difference between the large dose group and low dose group was significant(P0.05).Pathological sections stained with HE were observed by microscope,it showed no changes among groups.Conclusion Qingfei Kangfu Mixturecan relieve the hormone dependent dermatitis in guinea pigs." @default.
- W2386060632 created "2016-06-24" @default.
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- W2386060632 date "2012-01-01" @default.
- W2386060632 modified "2023-09-22" @default.
- W2386060632 title "Experimental study on Qingfei Kangfu Mixture for hormone-dependent dermatitis in guinea pig models" @default.
- W2386060632 hasPublicationYear "2012" @default.
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