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- W2386074028 abstract "Objective To investigate the stability of compatibility of polyene phosphatidylcholine and reduced glutathione,succinic acid-adenosylmethionine,fructose sodium diphosphate,vitamin C,and the causes and nature of the incompatibity. Methods A HPLC method was applied to determine the concentration of polyene phosphatidylcholine in the mixture with different density and to observe the change of mixture at the appearance,pH,particulate and concentration. The column was20RBAX Eclipse XDB-C18( 4. 6 mm × 150 mm,5μm),the mobil phase was methyl alcohol-Phosphoric acid( 40∶60),30 ℃,and detected wave-length was 205 nm,the flow rate was 1. 0 ml / min. Results Polyene phosphatidylcholine injection diluted with sodium chloride injection producted with turbidity,In the 24 hours polyene phosphateidylcholine had obvious change at the appearance,pH,particulate and concentration. Conclusion It has not stability that the mixture of polyene phosphatidylcholine and reduced glutathione; succinic acid-adenosylmethionine; fructose sodium diphosphate; Vitamin C. The Polyene phosphatidylcholine can not be compatible with injections such as reduced glutathione." @default.
- W2386074028 created "2016-06-24" @default.
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- W2386074028 date "2013-01-01" @default.
- W2386074028 modified "2023-09-22" @default.
- W2386074028 title "Stability of in-vitro compatibility of polyene phosphatidylcholine injection" @default.
- W2386074028 hasPublicationYear "2013" @default.
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