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- W2386078492 abstract "OBJECTIVE To explore the MMP1,MMP2,MMP9 and TIMP-1,TIMP-2in patients with gliomas in the expression and detection of brain glioma:a clinical diagnostic value.METHODS MMP1,MMP2,MMP9,TIMP-1 and TIMP-2 expression assay were detected in 38 patients with brain glioma and 20 cases without tumor craniocerebral operation patients.RESULTS In the control group,MMP1,MMP2,no MMP9 expression in patients with tumor did not show expression,and only one patient showed TIMP-1 and TIMP-2(+)expression.The positive rates of MMP1,MMP2,MMP9,TIMP-1 and TIMP-2 in cerebral glioma patients were 60.53%,60.53%,65.79%,57.90% and 55.26%,and along with the biology grade increased expression of positive rate would be increased tendency;In the low level group(I + II),the positive expression rates of MMP1,MMP2,MMP9,TIMP-1 and TIMP-2 were significantly lower than those of the high-level group(Ⅲ+ IV)(P﹤0.05);Speaman MMP1MMP2,correlation analysis,MMP9,TIMP-1,TIMP-2 and glioma malignancy has positive correlation(r = 0.251 7-0.621 1,P﹤0.05).CONCLUSION MMP1,MMP2,MMP9,TIMP-1 and TIMP-2 were closely association with brain glioma growth,which can reflect the degree of malignancy and invasiveness.These can be used for joint detection for the physician to determine the glioma malignancy and invasiveness." @default.
- W2386078492 created "2016-06-24" @default.
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- W2386078492 date "2012-01-01" @default.
- W2386078492 modified "2023-09-28" @default.
- W2386078492 title "MMP1,MMP2,MMP9 and TIMP-1,TIMP-2 in brain glioma diagnosis value" @default.
- W2386078492 hasPublicationYear "2012" @default.
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