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- W2386080267 abstract "To study the mutagenicity of compound sodium nitrophenolate,Ames test,erythrocyte micronucleus assay and spermatogonial chromosomal aberrations test were used.TA(97),TA(98),TA(100) and TA(102) strains were used in the Ames test(with or without S9 test) with doses of 1 000,500 and 250 μg/plate respectively.Medulla polychromatic erythrocyte micronucleus test was carried out with doses of 250,500 and 1 000 mg/kg respectively on male and female mice.Spermatogonial chromosome aberrance test was carried out with doses of 625,1 250 and 2 500 mg/kg respectively.Recovered strain numbers in different concentrations in the Ames test were not more than twice of the natural recovered strain numbers.No significant difference was found in the comparison between different dose groups with the negative group in the medulla polychromatic erythrocyte micronucleus test and spermatogonial chromosome aberrance test(P0.05).All test results are negative.Compound sodium nitrophenolate had no mutagenicity in this condition." @default.
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- W2386080267 date "2007-01-01" @default.
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- W2386080267 title "Study on Mutagenicity of Compound Sodium Nitrophenolate" @default.
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