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- W2386099143 abstract "Objective To investigate the release performance of gel matrices sustained release tablets based on hydrophilic resin Polyox-WSR. Methods The hydrophilic gel matrices sustained release tablets containing diltiazem hydrochlride as a model drug were obtained by direct compression method. The effects of release and release model were observed. Results The content and the viscosity of Polyox-WSR, the kind of lubricants, and the moisture content of the direct compression powder can influence the release of diltiazem hydrochlride from matrix tablets.The drug release pattern from the matrix tablets was approach to Higuchi and zero-order equation. Conclusion The Polyox-WSR can be used as a barrier to prepare a hydrophilic gel matrices sustained release tablets." @default.
- W2386099143 created "2016-06-24" @default.
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- W2386099143 date "2004-01-01" @default.
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- W2386099143 title "Study on compressed hydrophilic matrices tablets of Polyox-WSR" @default.
- W2386099143 hasPublicationYear "2004" @default.
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