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- W2386167976 abstract "Objective To investigate the effects of flumazenil on recovery and cognitive function in patients who were given propofol underwent painless gastroenterological endoscopy.Methods Seventy-five patients (aged 18 to 65 years, ASA Ⅰ or Ⅱ) scheduled for elective painless gastroenterological endoscopy were randomly given flumazenil 0.5 mg (group F1), flumazenil 1.0 mg (group F2), or normal saline (group C) intravenously after procedure. Anesthesia during procedure was maintained by fentanyl and TCI propofol infusion. BP,HR and SpO2 were monitored.The dosage of propofol, time of examination and incidence rates of bucking,body movement,hypoxemia,hypotension, bradycardia were recorded.The side effects such as bellyache,nausea and vomiting, shiver were also recorded.Cognitive function was assessed by the Mini-Mental State Examination (MMSE) and multi-functional electroencephalography before and 30 minutes after the procedure. The eye-opening time and waking time were recorded.Results The time of endoscopy, and total propofol consumption were comparable among three groups. Neither the recovery time including the eye-opening time and waking time nor the cognitive function such as MMSE scores,brain orientation index and SSI after the procedure revealed significant different among three groups.Conclusion Application of flumazenil could not decrease the recovery time or improve the cognitive function in patients for painless gastroenterological endoscopy procedure." @default.
- W2386167976 created "2016-06-24" @default.
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- W2386167976 date "2013-01-01" @default.
- W2386167976 modified "2023-09-24" @default.
- W2386167976 title "Effects of flumazenil on recovery and cognitive function in patients used propofol for painless gastroenterological endoscopy procedure" @default.
- W2386167976 hasPublicationYear "2013" @default.
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