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- W2386193945 abstract "OBJECTIVE:To evaluate the predicting abilities of the model for end-stage liver disease (MELD) to predict prognosis in pationts with primary bepatic cancer. METHODS: A cohort of 303 patients with primary hepatic cancer were retrospectively studied and followed up at least for one year. MELD score was calculated for each patient according to the modified formula by Kamath P.S., Child-Turcotte-Pugh (CTP) score and classification were calculated at the same time. The area under the receiver operating characteristic (ROC) curve (AUC) was used to compare MELD and CTP score and classification in predicting accuracy for different survival periods. Kaplan-Meier survival analysis was used to compare the mortality in subgroups ranked by the MELD score. RESULTS: The AUC values generated by the ROC curves for the MELD were 0.85 in predicting 3-month, and 0.78 for 1-year survival respectively, whereas the AUC values for CTP score and for CTP classification were 0.88, 0.81 in predicting 3-month, and 0.76, 0.73 for 1-year survival respectively. The differences of AUCs between the MELD and CTP score and classification were all not significant in predicting above period survival (P0.05). When the MELD score was greater than 20, the complications of portal hypertensions presented more significantly than that of MELD score less than 20, and the survival time and rate were significantly decreased (P=0.000). CONCLUSION: MELD is a good prognosis indictor in patients with primary hepatic cancer for short-term survival. The ability of prognosis of MELD is similar to Child-Turcotte-Pugh score and classification." @default.
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- W2386193945 date "2007-01-01" @default.
- W2386193945 modified "2023-09-23" @default.
- W2386193945 title "Prognostic value of the model for end-stage liver disease in patients with primary hepatic cancer" @default.
- W2386193945 hasPublicationYear "2007" @default.
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