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- W2386194080 abstract "Objective:To investigate the expression of costimulatory molecule B7-1 and B7-2 by warm ischemia/reperfusion(I/R)injury in rat liver and the meaning of immunology.Methods:Male Wistar rats were randomly divided into 3 groups:A(ischemia 30 mins,referfusion 24h),B(ischemia 60 mins,referfusion 24h),C(sham operation group).A model of hepatic warm I/R in rats was established according to the method of Ohmorid.The expression of B7-1 and B7-2 mRNA was analyzed by real-time reverse transcription polymerase chain reaction(RT-PCR).Results:Compared with the sham operation group,the expression of B7-1 and B7-2 mRNA increased significantly in the rats undergoing I/R procedure(P0.01).Conclusion:Warm ischemia/reperfusion injury may increase the immunogenicity of the liver by upregulating the costimulatory molecule B7-1 and B7-2." @default.
- W2386194080 created "2016-06-24" @default.
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- W2386194080 date "2006-01-01" @default.
- W2386194080 modified "2023-09-24" @default.
- W2386194080 title "Expression of costimulatory molecule B7-1 and B7-2 in warm ischemia/reperfusion(I/R) injury of liver in rats" @default.
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