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- W2386199325 abstract "The effects of vitamin E(VE)and enalapril(EN)on high glucose(HG)-induced the alteration of actin assembly were studied in rat glomerular mesangial celis (MC). Rat MC were cultured in high (30mmol/L) or normai )5.6 mmol/L, NG) glucose with or without VE or EN. The MC were labeled with fluorescent probes and fluorescence intensities were measured using con-focal laser scanning microscopy. MC incubated in HG, F-action bundles appeared less promi-nent and changed to irregular network, displaying partial disassemoly of F-actin.As compared with NG, HG caused a decrease in F-actin fluorescence intensity and an increase in G-actin intensity, consequently reducing the F/G-actin fluorescence intensity ratio. In HG, the addi-tion of VE or EN normalized HG-induced F-actin disassembly and F-and G-actin fluorescence intensities. These findings suggest that both VE and EN prevent HG-induced the al-teration of actin assembly pattern." @default.
- W2386199325 created "2016-06-24" @default.
- W2386199325 creator A5022057041 @default.
- W2386199325 date "1997-01-01" @default.
- W2386199325 modified "2023-09-23" @default.
- W2386199325 title "EFFECTS OF VITAMIN E AND ENALAPRIL ON HIGH GLUCOSE ALTERED ACTIN ASSEMBLY IN GLOMERULAR MESANGIAL CELLS" @default.
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