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- W2386202885 abstract "Objective:To study the significance of plasma growth differentiation factor 15(GDF-15),B-type natriuretic peptide(BNP) in patients with heart failure(HF) in Xinjiang Kazakans,and its relationship with the severity of HF.Method:There were 90 Kazaks patients with HF(NYHA Ⅱ~Ⅳ class) and 30 Kazaks patients with NYHA Ⅰ level included in the study.Fasting venous blood were taken to measure plasma GDF-15 and BNP levels,while heart indicators of echocardiography were measured for comparison.Result:The plasma levels of GDF-15 and BNP in HF group were significantly higher than those in the control group;and increased with NYHA class increasing,with statistically significant difference(P0.01).Plasma GDF-15 was positively correlated with Cr,LAD,LVEDd,NYHA class,BNP(r=0.266,0.423,0.668,0.925,0.845,P0.05),and negatively correlated with LVEF,FS(r=-0.807,-0.733,P0.01).Conclusion:The plasma GDF-15 and BNP levels are significantly higher in Kazaks patients with HF,and they are dependent on HF severity.Plasma GDF-15 level predicts the severity of Kazakh ethnic HF as a valuable indicator." @default.
- W2386202885 created "2016-06-24" @default.
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- W2386202885 date "2012-01-01" @default.
- W2386202885 modified "2023-09-23" @default.
- W2386202885 title "Clinical significance of Plasma growth differentiation factor 15 and B-type natriuretic peptide in patients with heart failure in Xinjiang Kazakans in China" @default.
- W2386202885 hasPublicationYear "2012" @default.
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