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- W2386241471 abstract "Objective To investigate the activity of immune evasion induced by a recombinant adenovirus vector expressing US3 gene in HL-7702 hepatic cells with transferred gene.Methods We first constructed an adenovirus vector expressing US3 gene and transferred it into HL7702 hepatic cells.Then immunological activities of US3 were determined by testing outivities of T lymphocytes(CTL)and natural killer(NK)cells.Results r-US3 and r-Track were successfully constructed.r-US3 could attenuate the activities of CTL and NK cells to HL-7720 cells with transferred gene.Conclusion The adenovirus vector expressing US3 gene might induce the activity of immune evasion in cells with transferred gene,attenuating immune rejection of host against transgened hepatic cells." @default.
- W2386241471 created "2016-06-24" @default.
- W2386241471 creator A5050111393 @default.
- W2386241471 date "2015-01-01" @default.
- W2386241471 modified "2023-09-27" @default.
- W2386241471 title "Attenuation on cytotoxic activities of T lymphocytes and NK cells against transgened hepatic cells by a recombinant adenovirus vector expressing US3 gene" @default.
- W2386241471 hasPublicationYear "2015" @default.
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